3FS4

Crystal structure determination of Ostrich hemoglobin at 2.2 Angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004601	molecular_function	peroxidase activity
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0031720	molecular_function	haptoglobin binding
A	0031838	cellular_component	haptoglobin-hemoglobin complex
A	0042744	biological_process	hydrogen peroxide catabolic process
A	0043177	molecular_function	organic acid binding
A	0046872	molecular_function	metal ion binding
A	0072562	cellular_component	blood microparticle
A	0098869	biological_process	cellular oxidant detoxification
B	0004601	molecular_function	peroxidase activity
B	0005344	molecular_function	oxygen carrier activity
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0031720	molecular_function	haptoglobin binding
B	0031838	cellular_component	haptoglobin-hemoglobin complex
B	0042744	biological_process	hydrogen peroxide catabolic process
B	0043177	molecular_function	organic acid binding
B	0046872	molecular_function	metal ion binding
B	0072562	cellular_component	blood microparticle
B	0098869	biological_process	cellular oxidant detoxification
C	0004601	molecular_function	peroxidase activity
C	0005344	molecular_function	oxygen carrier activity
C	0005506	molecular_function	iron ion binding
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0031720	molecular_function	haptoglobin binding
C	0031838	cellular_component	haptoglobin-hemoglobin complex
C	0042744	biological_process	hydrogen peroxide catabolic process
C	0043177	molecular_function	organic acid binding
C	0046872	molecular_function	metal ion binding
C	0072562	cellular_component	blood microparticle
C	0098869	biological_process	cellular oxidant detoxification
D	0004601	molecular_function	peroxidase activity
D	0005344	molecular_function	oxygen carrier activity
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0031720	molecular_function	haptoglobin binding
D	0031838	cellular_component	haptoglobin-hemoglobin complex
D	0042744	biological_process	hydrogen peroxide catabolic process
D	0043177	molecular_function	organic acid binding
D	0046872	molecular_function	metal ion binding
D	0072562	cellular_component	blood microparticle
D	0098869	biological_process	cellular oxidant detoxification

Functional Information from PDB Data

site_id	AC1
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM A 150

Chain	Residue
A	TYR42
A	VAL93
A	ASN97
A	PHE98
A	VAL132
A	LEU136
A	OXY151
A	HOH271
A	HOH307
A	PHE43
A	HIS45
A	HIS58
A	LYS61
A	ALA65
A	LEU86
A	HIS87
A	LEU91

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY A 151

Chain	Residue
A	HIS58
A	VAL62
A	HEM150

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM B 150

Chain	Residue
B	THR38
B	PHE41
B	PHE42
B	HIS63
B	SER70
B	PHE71
B	LEU88
B	HIS92
B	LEU96
B	ASN102
B	PHE103
B	LEU106
B	LEU141
B	OXY151
D	LYS120

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY B 151

Chain	Residue
B	HIS63
B	VAL67
B	HEM150

---

site_id	AC5
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM C 150

Chain	Residue
C	TYR42
C	PHE43
C	HIS45
C	HIS58
C	ALA65
C	LEU86
C	HIS87
C	LEU91
C	VAL93
C	PHE98
C	VAL132
C	LEU136
C	HOH149
C	OXY151
C	HOH157
C	HOH192

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY C 151

Chain	Residue
C	HIS58
C	VAL62
C	HEM150

---

site_id	AC7
Number of Residues	16
Details	BINDING SITE FOR RESIDUE HEM D 150

Chain	Residue
B	LYS120
D	PHE41
D	PHE42
D	HIS63
D	SER70
D	PHE71
D	LEU91
D	HIS92
D	LEU96
D	VAL98
D	ASN102
D	PHE103
D	LEU106
D	LEU141
D	OXY151
D	HOH401

---

site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE OXY D 151

Chain	Residue
D	HIS63
D	VAL67
D	HEM150

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	BINDING: distal binding residue

Chain	Residue	Details
B	HIS63
D	HIS63

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: proximal binding residue

Chain	Residue	Details
B	HIS92
D	HIS92

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