3FKY
Crystal structure of the glutamine synthetase Gln1deltaN18 from the yeast Saccharomyces cerevisiae
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004356 | molecular_function | glutamine synthetase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0006542 | biological_process | glutamine biosynthetic process |
A | 0016874 | molecular_function | ligase activity |
A | 0034399 | cellular_component | nuclear periphery |
B | 0003824 | molecular_function | catalytic activity |
B | 0004356 | molecular_function | glutamine synthetase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0005634 | cellular_component | nucleus |
B | 0005737 | cellular_component | cytoplasm |
B | 0006542 | biological_process | glutamine biosynthetic process |
B | 0016874 | molecular_function | ligase activity |
B | 0034399 | cellular_component | nuclear periphery |
C | 0003824 | molecular_function | catalytic activity |
C | 0004356 | molecular_function | glutamine synthetase activity |
C | 0005524 | molecular_function | ATP binding |
C | 0005634 | cellular_component | nucleus |
C | 0005737 | cellular_component | cytoplasm |
C | 0006542 | biological_process | glutamine biosynthetic process |
C | 0016874 | molecular_function | ligase activity |
C | 0034399 | cellular_component | nuclear periphery |
D | 0003824 | molecular_function | catalytic activity |
D | 0004356 | molecular_function | glutamine synthetase activity |
D | 0005524 | molecular_function | ATP binding |
D | 0005634 | cellular_component | nucleus |
D | 0005737 | cellular_component | cytoplasm |
D | 0006542 | biological_process | glutamine biosynthetic process |
D | 0016874 | molecular_function | ligase activity |
D | 0034399 | cellular_component | nuclear periphery |
E | 0003824 | molecular_function | catalytic activity |
E | 0004356 | molecular_function | glutamine synthetase activity |
E | 0005524 | molecular_function | ATP binding |
E | 0005634 | cellular_component | nucleus |
E | 0005737 | cellular_component | cytoplasm |
E | 0006542 | biological_process | glutamine biosynthetic process |
E | 0016874 | molecular_function | ligase activity |
E | 0034399 | cellular_component | nuclear periphery |
F | 0003824 | molecular_function | catalytic activity |
F | 0004356 | molecular_function | glutamine synthetase activity |
F | 0005524 | molecular_function | ATP binding |
F | 0005634 | cellular_component | nucleus |
F | 0005737 | cellular_component | cytoplasm |
F | 0006542 | biological_process | glutamine biosynthetic process |
F | 0016874 | molecular_function | ligase activity |
F | 0034399 | cellular_component | nuclear periphery |
G | 0003824 | molecular_function | catalytic activity |
G | 0004356 | molecular_function | glutamine synthetase activity |
G | 0005524 | molecular_function | ATP binding |
G | 0005634 | cellular_component | nucleus |
G | 0005737 | cellular_component | cytoplasm |
G | 0006542 | biological_process | glutamine biosynthetic process |
G | 0016874 | molecular_function | ligase activity |
G | 0034399 | cellular_component | nuclear periphery |
H | 0003824 | molecular_function | catalytic activity |
H | 0004356 | molecular_function | glutamine synthetase activity |
H | 0005524 | molecular_function | ATP binding |
H | 0005634 | cellular_component | nucleus |
H | 0005737 | cellular_component | cytoplasm |
H | 0006542 | biological_process | glutamine biosynthetic process |
H | 0016874 | molecular_function | ligase activity |
H | 0034399 | cellular_component | nuclear periphery |
I | 0003824 | molecular_function | catalytic activity |
I | 0004356 | molecular_function | glutamine synthetase activity |
I | 0005524 | molecular_function | ATP binding |
I | 0005634 | cellular_component | nucleus |
I | 0005737 | cellular_component | cytoplasm |
I | 0006542 | biological_process | glutamine biosynthetic process |
I | 0016874 | molecular_function | ligase activity |
I | 0034399 | cellular_component | nuclear periphery |
J | 0003824 | molecular_function | catalytic activity |
J | 0004356 | molecular_function | glutamine synthetase activity |
J | 0005524 | molecular_function | ATP binding |
J | 0005634 | cellular_component | nucleus |
J | 0005737 | cellular_component | cytoplasm |
J | 0006542 | biological_process | glutamine biosynthetic process |
J | 0016874 | molecular_function | ligase activity |
J | 0034399 | cellular_component | nuclear periphery |
K | 0003824 | molecular_function | catalytic activity |
K | 0004356 | molecular_function | glutamine synthetase activity |
K | 0005524 | molecular_function | ATP binding |
K | 0005634 | cellular_component | nucleus |
K | 0005737 | cellular_component | cytoplasm |
K | 0006542 | biological_process | glutamine biosynthetic process |
K | 0016874 | molecular_function | ligase activity |
K | 0034399 | cellular_component | nuclear periphery |
L | 0003824 | molecular_function | catalytic activity |
L | 0004356 | molecular_function | glutamine synthetase activity |
L | 0005524 | molecular_function | ATP binding |
L | 0005634 | cellular_component | nucleus |
L | 0005737 | cellular_component | cytoplasm |
L | 0006542 | biological_process | glutamine biosynthetic process |
L | 0016874 | molecular_function | ligase activity |
L | 0034399 | cellular_component | nuclear periphery |
M | 0003824 | molecular_function | catalytic activity |
M | 0004356 | molecular_function | glutamine synthetase activity |
M | 0005524 | molecular_function | ATP binding |
M | 0005634 | cellular_component | nucleus |
M | 0005737 | cellular_component | cytoplasm |
M | 0006542 | biological_process | glutamine biosynthetic process |
M | 0016874 | molecular_function | ligase activity |
M | 0034399 | cellular_component | nuclear periphery |
N | 0003824 | molecular_function | catalytic activity |
N | 0004356 | molecular_function | glutamine synthetase activity |
N | 0005524 | molecular_function | ATP binding |
N | 0005634 | cellular_component | nucleus |
N | 0005737 | cellular_component | cytoplasm |
N | 0006542 | biological_process | glutamine biosynthetic process |
N | 0016874 | molecular_function | ligase activity |
N | 0034399 | cellular_component | nuclear periphery |
O | 0003824 | molecular_function | catalytic activity |
O | 0004356 | molecular_function | glutamine synthetase activity |
O | 0005524 | molecular_function | ATP binding |
O | 0005634 | cellular_component | nucleus |
O | 0005737 | cellular_component | cytoplasm |
O | 0006542 | biological_process | glutamine biosynthetic process |
O | 0016874 | molecular_function | ligase activity |
O | 0034399 | cellular_component | nuclear periphery |
P | 0003824 | molecular_function | catalytic activity |
P | 0004356 | molecular_function | glutamine synthetase activity |
P | 0005524 | molecular_function | ATP binding |
P | 0005634 | cellular_component | nucleus |
P | 0005737 | cellular_component | cytoplasm |
P | 0006542 | biological_process | glutamine biosynthetic process |
P | 0016874 | molecular_function | ligase activity |
P | 0034399 | cellular_component | nuclear periphery |
Q | 0003824 | molecular_function | catalytic activity |
Q | 0004356 | molecular_function | glutamine synthetase activity |
Q | 0005524 | molecular_function | ATP binding |
Q | 0005634 | cellular_component | nucleus |
Q | 0005737 | cellular_component | cytoplasm |
Q | 0006542 | biological_process | glutamine biosynthetic process |
Q | 0016874 | molecular_function | ligase activity |
Q | 0034399 | cellular_component | nuclear periphery |
R | 0003824 | molecular_function | catalytic activity |
R | 0004356 | molecular_function | glutamine synthetase activity |
R | 0005524 | molecular_function | ATP binding |
R | 0005634 | cellular_component | nucleus |
R | 0005737 | cellular_component | cytoplasm |
R | 0006542 | biological_process | glutamine biosynthetic process |
R | 0016874 | molecular_function | ligase activity |
R | 0034399 | cellular_component | nuclear periphery |
S | 0003824 | molecular_function | catalytic activity |
S | 0004356 | molecular_function | glutamine synthetase activity |
S | 0005524 | molecular_function | ATP binding |
S | 0005634 | cellular_component | nucleus |
S | 0005737 | cellular_component | cytoplasm |
S | 0006542 | biological_process | glutamine biosynthetic process |
S | 0016874 | molecular_function | ligase activity |
S | 0034399 | cellular_component | nuclear periphery |
T | 0003824 | molecular_function | catalytic activity |
T | 0004356 | molecular_function | glutamine synthetase activity |
T | 0005524 | molecular_function | ATP binding |
T | 0005634 | cellular_component | nucleus |
T | 0005737 | cellular_component | cytoplasm |
T | 0006542 | biological_process | glutamine biosynthetic process |
T | 0016874 | molecular_function | ligase activity |
T | 0034399 | cellular_component | nuclear periphery |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FLC A 371 |
Chain | Residue |
A | GLU133 |
A | GLU193 |
A | GLN198 |
A | ASN245 |
A | GLY246 |
A | ALA247 |
A | HIS250 |
A | ARG292 |
A | ARG333 |
site_id | AC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC B 371 |
Chain | Residue |
B | GLU133 |
B | GLU193 |
B | GLN198 |
B | ASN245 |
B | GLY246 |
B | ALA247 |
B | HIS250 |
B | ARG292 |
site_id | AC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FLC C 371 |
Chain | Residue |
C | GLU133 |
C | GLU193 |
C | GLN198 |
C | ASN245 |
C | GLY246 |
C | ALA247 |
C | GLY248 |
C | HIS250 |
C | ARG292 |
site_id | AC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC D 371 |
Chain | Residue |
D | GLU133 |
D | GLU193 |
D | GLN198 |
D | ASN245 |
D | GLY246 |
D | ALA247 |
D | HIS250 |
D | ARG292 |
site_id | AC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC E 371 |
Chain | Residue |
E | GLU133 |
E | GLN198 |
E | ASN245 |
E | GLY246 |
E | ALA247 |
E | GLY248 |
E | HIS250 |
E | ARG292 |
site_id | AC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC F 371 |
Chain | Residue |
F | GLU133 |
F | GLU193 |
F | GLN198 |
F | ASN245 |
F | GLY246 |
F | ALA247 |
F | HIS250 |
F | ARG292 |
site_id | AC7 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FLC G 371 |
Chain | Residue |
G | GLU133 |
G | GLU193 |
G | GLN198 |
G | ASN245 |
G | GLY246 |
G | HIS250 |
G | ARG292 |
site_id | AC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE FLC H 371 |
Chain | Residue |
H | GLU133 |
H | GLU193 |
H | GLN198 |
H | GLY246 |
H | ALA247 |
H | HIS250 |
H | ARG292 |
site_id | AC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC I 371 |
Chain | Residue |
I | GLU133 |
I | GLU193 |
I | GLN198 |
I | ASN245 |
I | GLY246 |
I | ALA247 |
I | HIS250 |
I | ARG292 |
site_id | BC1 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC J 371 |
Chain | Residue |
J | GLU133 |
J | GLU193 |
J | GLN198 |
J | ASN245 |
J | GLY246 |
J | ALA247 |
J | HIS250 |
J | ARG292 |
site_id | BC2 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE FLC K 371 |
Chain | Residue |
K | GLU133 |
K | GLU193 |
K | GLN198 |
K | ASN245 |
K | GLY246 |
K | ALA247 |
K | GLY248 |
K | HIS250 |
K | ARG292 |
K | ARG333 |
site_id | BC3 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FLC L 371 |
Chain | Residue |
L | GLU133 |
L | GLU193 |
L | GLN198 |
L | ASN245 |
L | GLY246 |
L | ALA247 |
L | HIS250 |
L | ARG292 |
L | ARG333 |
site_id | BC4 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC M 371 |
Chain | Residue |
M | GLU133 |
M | GLU193 |
M | GLN198 |
M | ASN245 |
M | GLY246 |
M | ALA247 |
M | HIS250 |
M | ARG292 |
site_id | BC5 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC N 371 |
Chain | Residue |
N | GLU133 |
N | GLU193 |
N | GLN198 |
N | ASN245 |
N | GLY246 |
N | ALA247 |
N | HIS250 |
N | ARG292 |
site_id | BC6 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC O 371 |
Chain | Residue |
O | GLU133 |
O | GLU193 |
O | GLN198 |
O | ASN245 |
O | GLY246 |
O | ALA247 |
O | HIS250 |
O | ARG292 |
site_id | BC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC P 371 |
Chain | Residue |
P | GLU133 |
P | GLU193 |
P | GLN198 |
P | ASN245 |
P | GLY246 |
P | ALA247 |
P | HIS250 |
P | ARG292 |
site_id | BC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC Q 371 |
Chain | Residue |
Q | GLU133 |
Q | GLU193 |
Q | GLN198 |
Q | ASN245 |
Q | GLY246 |
Q | HIS250 |
Q | ARG292 |
Q | ARG333 |
site_id | BC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC R 371 |
Chain | Residue |
R | GLU133 |
R | GLU193 |
R | GLN198 |
R | ASN245 |
R | GLY246 |
R | HIS250 |
R | ARG292 |
R | ARG333 |
site_id | CC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE FLC S 371 |
Chain | Residue |
S | GLU133 |
S | GLU193 |
S | GLN198 |
S | ASN245 |
S | GLY246 |
S | ALA247 |
S | GLY248 |
S | HIS250 |
S | ARG292 |
site_id | CC2 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE FLC T 371 |
Chain | Residue |
T | GLU133 |
T | GLU193 |
T | GLN198 |
T | ASN245 |
T | GLY246 |
T | ALA247 |
T | HIS250 |
T | ARG292 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 20 |
Details | MOD_RES: N-acetylalanine => ECO:0000269|PubMed:9298649, ECO:0007744|PubMed:15665377, ECO:0007744|PubMed:22814378 |
Chain | Residue | Details |
A | ALA2 | |
J | ALA2 | |
K | ALA2 | |
L | ALA2 | |
M | ALA2 | |
N | ALA2 | |
O | ALA2 | |
P | ALA2 | |
Q | ALA2 | |
R | ALA2 | |
S | ALA2 | |
B | ALA2 | |
T | ALA2 | |
C | ALA2 | |
D | ALA2 | |
E | ALA2 | |
F | ALA2 | |
G | ALA2 | |
H | ALA2 | |
I | ALA2 |
site_id | SWS_FT_FI2 |
Number of Residues | 20 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:15665377 |
Chain | Residue | Details |
A | SER5 | |
J | SER5 | |
K | SER5 | |
L | SER5 | |
M | SER5 | |
N | SER5 | |
O | SER5 | |
P | SER5 | |
Q | SER5 | |
R | SER5 | |
S | SER5 | |
B | SER5 | |
T | SER5 | |
C | SER5 | |
D | SER5 | |
E | SER5 | |
F | SER5 | |
G | SER5 | |
H | SER5 | |
I | SER5 |
site_id | SWS_FT_FI3 |
Number of Residues | 80 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
Chain | Residue | Details |
A | LYS283 | |
C | LYS324 | |
C | LYS363 | |
D | LYS283 | |
D | LYS324 | |
D | LYS363 | |
E | LYS283 | |
E | LYS324 | |
E | LYS363 | |
F | LYS283 | |
F | LYS324 | |
F | LYS363 | |
G | LYS283 | |
G | LYS324 | |
G | LYS363 | |
H | LYS283 | |
A | LYS324 | |
H | LYS324 | |
H | LYS363 | |
I | LYS283 | |
I | LYS324 | |
I | LYS363 | |
J | LYS283 | |
J | LYS324 | |
A | LYS363 | |
J | LYS363 | |
K | LYS283 | |
K | LYS324 | |
K | LYS363 | |
L | LYS283 | |
L | LYS324 | |
L | LYS363 | |
M | LYS283 | |
B | LYS283 | |
M | LYS324 | |
M | LYS363 | |
N | LYS283 | |
N | LYS324 | |
N | LYS363 | |
O | LYS283 | |
O | LYS324 | |
O | LYS363 | |
P | LYS283 | |
P | LYS324 | |
P | LYS363 | |
Q | LYS283 | |
Q | LYS324 | |
Q | LYS363 | |
R | LYS283 | |
B | LYS324 | |
R | LYS324 | |
R | LYS363 | |
S | LYS283 | |
S | LYS324 | |
S | LYS363 | |
T | LYS283 | |
T | LYS324 | |
B | LYS363 | |
T | LYS363 | |
C | LYS283 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
A | ASP60 | |
A | ARG312 |
site_id | CSA10 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
J | ASP60 | |
J | ARG312 |
site_id | CSA11 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
K | ASP60 | |
K | ARG312 |
site_id | CSA12 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
L | ASP60 | |
L | ARG312 |
site_id | CSA13 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
M | ASP60 | |
M | ARG312 |
site_id | CSA14 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
N | ASP60 | |
N | ARG312 |
site_id | CSA15 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
O | ASP60 | |
O | ARG312 |
site_id | CSA16 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
P | ASP60 | |
P | ARG312 |
site_id | CSA17 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
Q | ASP60 | |
Q | ARG312 |
site_id | CSA18 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
R | ASP60 | |
R | ARG312 |
site_id | CSA19 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
S | ASP60 | |
S | ARG312 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
B | ASP60 | |
B | ARG312 |
site_id | CSA20 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
T | ASP60 | |
T | ARG312 |
site_id | CSA3 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
C | ASP60 | |
C | ARG312 |
site_id | CSA4 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
D | ASP60 | |
D | ARG312 |
site_id | CSA5 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
E | ASP60 | |
E | ARG312 |
site_id | CSA6 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
F | ASP60 | |
F | ARG312 |
site_id | CSA7 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
G | ASP60 | |
G | ARG312 |
site_id | CSA8 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
H | ASP60 | |
H | ARG312 |
site_id | CSA9 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1hto |
Chain | Residue | Details |
I | ASP60 | |
I | ARG312 |