3FK2

Crystal structure of the RhoGAP domain of human glucocorticoid receptor DNA-binding factor 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007165	biological_process	signal transduction
B	0007165	biological_process	signal transduction
C	0007165	biological_process	signal transduction
D	0007165	biological_process	signal transduction

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE UNX A 1

Chain	Residue
A	THR1313

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE UNX B 2

Chain	Residue
B	THR1313

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE UNX C 3

Chain	Residue
C	THR1313

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site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE UNX D 4

Chain	Residue
D	THR1313

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site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE UNX A 5

Chain	Residue
C	PHE1434
A	GLN1431
C	UNX7
C	GLN1430
C	GLN1431
C	PRO1433

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site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE UNX B 6

Chain	Residue
B	GLN1431
D	UNX8
D	GLN1431
D	PRO1433
D	PHE1434

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site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE UNX C 7

Chain	Residue
A	UNX5
A	GLN1431
A	PRO1433
A	PHE1434
C	GLN1431
C	PHE1434

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE UNX D 8

Chain	Residue
B	UNX6
B	GLN1431
B	PRO1433
B	PHE1434
D	GLN1431

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	561
Details	Domain: {"description":"Rho-GAP","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Site: {"description":"Arginine finger; crucial for GTP hydrolysis by stabilizing the transition state","evidences":[{"source":"PROSITE-ProRule","id":"PRU00172","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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