3FHG
Crystal structure of Sulfolobus solfataricus 8-oxoguanine DNA glycosylase (SsOgg)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003906 | molecular_function | DNA-(apurinic or apyrimidinic site) endonuclease activity |
| A | 0006281 | biological_process | DNA repair |
| A | 0006284 | biological_process | base-excision repair |
| A | 0006974 | biological_process | DNA damage response |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0016829 | molecular_function | lyase activity |
| A | 0140078 | molecular_function | class I DNA-(apurinic or apyrimidinic site) endonuclease activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 208 |
| Chain | Residue |
| A | HIS132 |
| A | ARG135 |
| A | ASP194 |
| A | TRP198 |
| A | VAL206 |
| A | LYS207 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 209 |
| Chain | Residue |
| A | ARG35 |
| A | TYR52 |
| A | LYS207 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 210 |
| Chain | Residue |
| A | ASN29 |
| A | GLU30 |
| A | LYS101 |
| A | SO4216 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 211 |
| Chain | Residue |
| A | MET188 |
| A | SER189 |
| A | ILE192 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 212 |
| Chain | Residue |
| A | GLU110 |
| A | ASP111 |
| A | GLN112 |
| A | GLN113 |
| A | ASP141 |
| A | HOH270 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 213 |
| Chain | Residue |
| A | ASN8 |
| A | LYS10 |
| A | LYS75 |
| A | TYR82 |
| A | ASN83 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 214 |
| Chain | Residue |
| A | GLU117 |
| A | ARG118 |
| A | ASN121 |
| site_id | AC8 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 215 |
| Chain | Residue |
| A | ARG14 |
| A | ARG14 |
| A | ASN203 |
| A | THR204 |
| A | THR204 |
| A | ILE205 |
| A | ILE205 |
| A | HOH248 |
| A | HOH248 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 216 |
| Chain | Residue |
| A | ASN26 |
| A | LEU27 |
| A | LYS101 |
| A | LYS105 |
| A | GOL210 |
| A | HOH285 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 217 |
| Chain | Residue |
| A | GLY59 |
| A | GLN60 |
| A | HOH281 |
| A | HOH287 |
| A | HOH291 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 218 |
| Chain | Residue |
| A | LYS61 |
| A | GLY160 |
| A | GLU161 |
| A | HOH282 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 219 |
| Chain | Residue |
| A | HOH295 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 220 |
| Chain | Residue |
| A | ARG147 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 221 |
| Chain | Residue |
| A | SER168 |
| A | LYS169 |
| site_id | BC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 222 |
| Chain | Residue |
| A | ARG23 |
| A | PHE140 |
| A | SER189 |
| A | HOH238 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00241","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19446526","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Site: {"description":"Important for guanine/8-oxoguanine distinction","evidences":[{"source":"HAMAP-Rule","id":"MF_00241","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"19446526","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
