3F6Y

Conformational Closure of the Catalytic Site of Human CD38 Induced by Calcium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0061809	molecular_function	NAD+ nucleotidase, cyclic ADP-ribose generating

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 1

Chain	Residue
A	HOH5
A	HOH8
A	HOH10
A	CYS99

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 2

Chain	Residue
A	HOH396
A	HOH25
A	GLU72
A	THR144
A	ASP147
A	HOH318

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CA A 3

Chain	Residue
A	ARG127

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000305|PubMed:7961800

Chain	Residue	Details
A	CYS119
A	CYS201

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218

Chain	Residue	Details
A	ASP100
A	ASP209

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site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASP164

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site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218, ECO:0000269|PubMed:19349973

Chain	Residue	Details
A	ASP219

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1r16

Chain	Residue	Details
A	GLU226
A	GLU146

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