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3F6G

Crystal structure of the regulatory domain of LiCMS in complexed with isoleucine - type II

Functional Information from GO Data
ChainGOidnamespacecontents
A0003852molecular_function2-isopropylmalate synthase activity
A0009098biological_processL-leucine biosynthetic process
B0003852molecular_function2-isopropylmalate synthase activity
B0009098biological_processL-leucine biosynthetic process
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE ZN B 358
ChainResidue
BHOH104
BHOH104
BHIS400
BHIS400
BHIS408
BHIS408

site_idAC2
Number of Residues12
DetailsBINDING SITE FOR RESIDUE ILE B 1
ChainResidue
ATYR430
AASP431
BTHR464
BASP465
BALA466
BVAL468
BPRO493
BASP494
BGLN495
AHOH27
AGLY428
AGLY429

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 B 1004
ChainResidue
BHOH10
BTYR415
BGLN416
BLYS418
BLEU444

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 B 1005
ChainResidue
BHOH3
BHOH129
BARG471
BLYS487
BMET489

site_idAC5
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 1006
ChainResidue
BVAL491
BHIS501
BLYS505

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 1007
ChainResidue
AHOH40
AHIS492
BHOH53
BILE403

site_idAC7
Number of Residues6
DetailsBINDING SITE FOR RESIDUE ZN A 359
ChainResidue
AHOH143
AHOH143
AHIS400
AHIS400
AHIS408
AHIS408

site_idAC8
Number of Residues12
DetailsBINDING SITE FOR RESIDUE ILE A 1
ChainResidue
AHOH6
ALYS463
ATHR464
AASP465
AALA466
APRO493
AASP494
AGLN495
BGLY428
BTYR430
BASP431
BTYR454

site_idAC9
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 1001
ChainResidue
AHOH22
AHOH81
ALYS450
ALEU451
BLYS463
BTHR464

site_idBC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 1002
ChainResidue
AGLY402
AILE403
AGLY404
AILE405
BHIS492

site_idBC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 1003
ChainResidue
AHOH115
AGLY490
AVAL491
AHIS501
ALYS505

site_idBC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 1008
ChainResidue
AHOH112
APRO459
APRO460
BTHR485

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PDB entries from 2024-11-06

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