3F4N

Crystal Structure of Pyridoxal Phosphate Biosynthetic Protein PdxJ from Yersinia pestis

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008615	biological_process	pyridoxine biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016769	molecular_function	transferase activity, transferring nitrogenous groups
A	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0008615	biological_process	pyridoxine biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016769	molecular_function	transferase activity, transferring nitrogenous groups
B	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0008615	biological_process	pyridoxine biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016769	molecular_function	transferase activity, transferring nitrogenous groups
C	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0008615	biological_process	pyridoxine biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016769	molecular_function	transferase activity, transferring nitrogenous groups
D	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0008615	biological_process	pyridoxine biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016769	molecular_function	transferase activity, transferring nitrogenous groups
E	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0008615	biological_process	pyridoxine biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016769	molecular_function	transferase activity, transferring nitrogenous groups
F	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0008615	biological_process	pyridoxine biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016769	molecular_function	transferase activity, transferring nitrogenous groups
G	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity
H	0005737	cellular_component	cytoplasm
H	0005829	cellular_component	cytosol
H	0008615	biological_process	pyridoxine biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016769	molecular_function	transferase activity, transferring nitrogenous groups
H	0033856	molecular_function	pyridoxine 5'-phosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	BINDING SITE FOR RESIDUE PXP A 501

Chain	Residue
A	ASN9
A	GLY215
A	HIS216
A	HOH1046
A	HOH1177
A	HOH1353
A	HOH1439
B	ARG20
A	GLU72
A	VAL94
A	PHE133
A	GLU153
A	HIS193
A	GLY194
A	ASN213
A	ILE214

---

site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PXP B 502

Chain	Residue
A	ARG20
B	ASN9
B	GLU72
B	VAL94
B	PHE133
B	GLU153
B	HIS193
B	GLY194
B	ASN213
B	ILE214
B	GLY215
B	HIS216
B	HOH1048
B	HOH1091
B	HOH1312

---

site_id	AC3
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PXP C 503

Chain	Residue
C	ASN9
C	GLU72
C	PHE133
C	GLU153
C	HIS193
C	GLY194
C	ASN213
C	ILE214
C	GLY215
C	HIS216
C	HOH1191
C	HOH1306
C	HOH1595
C	HOH1623
D	ARG20

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PXP D 504

Chain	Residue
C	ARG20
D	GLU72
D	VAL94
D	PHE133
D	GLU153
D	HIS193
D	GLY194
D	ASN213
D	ILE214
D	GLY215
D	HIS216
D	HOH1001
D	HOH1184
D	HOH1214
D	HOH1581

---

site_id	AC5
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PXP E 505

Chain	Residue
E	ASN9
E	GLU72
E	PHE133
E	GLU153
E	HIS193
E	GLY194
E	ASN213
E	ILE214
E	GLY215
E	HIS216
E	HOH1083
E	HOH1567
E	HOH1626
F	ARG20

---

site_id	AC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PXP F 506

Chain	Residue
E	ARG20
E	SO4602
F	GLU72
F	PHE133
F	GLU153
F	HIS193
F	GLY194
F	ASN213
F	ILE214
F	GLY215
F	HIS216
F	HOH1188
F	HOH1235
F	HOH1244
F	HOH1538

---

site_id	AC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PXP G 507

Chain	Residue
G	HOH1352
G	HOH1518
G	HOH1519
G	HOH1617
G	HOH1627
H	ARG20
G	GLU72
G	PHE133
G	GLU153
G	HIS193
G	GLY194
G	ASN213
G	ILE214
G	GLY215
G	HIS216

---

site_id	AC8
Number of Residues	14
Details	BINDING SITE FOR RESIDUE PXP H 508

Chain	Residue
G	ARG20
H	GLU72
H	VAL94
H	PHE133
H	GLU153
H	HIS193
H	GLY194
H	ASN213
H	ILE214
H	GLY215
H	HIS216
H	HOH1115
H	HOH1245
H	HOH1493

---

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 601

Chain	Residue
C	HIS12
C	ARG47
C	ARG51
C	HIS52
C	HOH1191
C	HOH1624
D	ARG20

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E 602

Chain	Residue
E	ARG20
E	HOH1539
F	HIS12
F	HIS52
F	PXP506
F	HOH1389
F	HOH1556

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 E 603

Chain	Residue
E	HIS12
E	ARG47
E	ARG51
E	HIS52
F	ARG20

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_00279","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00279","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	63
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00279","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"HAMAP-Rule","id":"MF_00279","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---