3F2R
Crystal structure of human choline kinase alpha in complex with hemicholinium-3
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HC6 A 603 |
| Chain | Residue |
| A | ASP306 |
| A | TYR440 |
| A | GLN308 |
| A | TYR333 |
| A | TYR354 |
| A | PHE361 |
| A | TRP420 |
| A | TRP423 |
| A | GLU434 |
| A | PHE435 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 606 |
| Chain | Residue |
| A | GLU309 |
| A | GLU349 |
| A | TYR352 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE HC6 B 603 |
| Chain | Residue |
| B | ASP306 |
| B | GLN308 |
| B | TYR333 |
| B | TYR354 |
| B | PHE361 |
| B | TRP420 |
| B | ILE433 |
| B | GLU434 |
| B | PHE435 |
| B | TYR440 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX B 606 |
| Chain | Residue |
| B | GLU309 |
| B | GLU349 |
| B | TYR352 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 1 |
| Chain | Residue |
| A | HOH19 |
| A | TYR437 |
| A | MET438 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX B 2 |
| Chain | Residue |
| B | ARG270 |
| B | TYR437 |
| B | MET438 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17007874","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20299452","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CKP","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3G15","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17007874","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CKQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"34077757","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"34077757","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1l8t |
| Chain | Residue | Details |
| A | ASP306 | |
| A | ARG146 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1l8t |
| Chain | Residue | Details |
| B | ASP306 |
