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3F1R

Crystal structure of FGF20 dimer

Functional Information from GO Data
ChainGOidnamespacecontents
A0005102molecular_functionsignaling receptor binding
A0005104molecular_functionfibroblast growth factor receptor binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0007165biological_processsignal transduction
A0007267biological_processcell-cell signaling
A0008083molecular_functiongrowth factor activity
A0008284biological_processpositive regulation of cell population proliferation
A0008543biological_processfibroblast growth factor receptor signaling pathway
A0014059biological_processregulation of dopamine secretion
A0022008biological_processneurogenesis
A0030334biological_processregulation of cell migration
A0043395molecular_functionheparan sulfate proteoglycan binding
A0043410biological_processpositive regulation of MAPK cascade
A0043524biological_processnegative regulation of neuron apoptotic process
A0045664biological_processregulation of neuron differentiation
A0090722molecular_functionreceptor-receptor interaction
A1904340biological_processpositive regulation of dopaminergic neuron differentiation
B0005102molecular_functionsignaling receptor binding
B0005104molecular_functionfibroblast growth factor receptor binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0007165biological_processsignal transduction
B0007267biological_processcell-cell signaling
B0008083molecular_functiongrowth factor activity
B0008284biological_processpositive regulation of cell population proliferation
B0008543biological_processfibroblast growth factor receptor signaling pathway
B0014059biological_processregulation of dopamine secretion
B0022008biological_processneurogenesis
B0030334biological_processregulation of cell migration
B0043395molecular_functionheparan sulfate proteoglycan binding
B0043410biological_processpositive regulation of MAPK cascade
B0043524biological_processnegative regulation of neuron apoptotic process
B0045664biological_processregulation of neuron differentiation
B0090722molecular_functionreceptor-receptor interaction
B1904340biological_processpositive regulation of dopaminergic neuron differentiation
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 A 301
ChainResidue
AARG140
ALYS157
AARG164

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 A 302
ChainResidue
AARG163
AARG164
AARG180
AARG183

site_idAC3
Number of Residues2
DetailsBINDING SITE FOR RESIDUE SO4 A 303
ChainResidue
AARG180
ALYS182

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 300
ChainResidue
BARG1163
BARG1164
BARG1180
BARG1183

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B 304
ChainResidue
BARG1176
BARG1180
BLYS1182
BLYS1182

site_idAC6
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B 305
ChainResidue
BARG1140
BLYS1157
BARG1164

Functional Information from PROSITE/UniProt
site_idPS00247
Number of Residues24
DetailsHBGF_FGF HBGF/FGF family signature. GeLyGseklts.ECiFrEqfeenwY
ChainResidueDetails
AGLY125-TYR148

247536

PDB entries from 2026-01-14

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