3EXE
Crystal structure of the pyruvate dehydrogenase (E1p) component of human pyruvate dehydrogenase complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005759 | cellular_component | mitochondrial matrix |
| A | 0006006 | biological_process | glucose metabolic process |
| A | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| A | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005759 | cellular_component | mitochondrial matrix |
| B | 0006006 | biological_process | glucose metabolic process |
| B | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0009060 | biological_process | aerobic respiration |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0044272 | biological_process | sulfur compound biosynthetic process |
| B | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0072522 | biological_process | purine-containing compound biosynthetic process |
| C | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005759 | cellular_component | mitochondrial matrix |
| C | 0006006 | biological_process | glucose metabolic process |
| C | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| C | 0006099 | biological_process | tricarboxylic acid cycle |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| C | 0032991 | cellular_component | protein-containing complex |
| C | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| C | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0005739 | cellular_component | mitochondrion |
| D | 0005759 | cellular_component | mitochondrial matrix |
| D | 0006006 | biological_process | glucose metabolic process |
| D | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| D | 0006099 | biological_process | tricarboxylic acid cycle |
| D | 0009060 | biological_process | aerobic respiration |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0044272 | biological_process | sulfur compound biosynthetic process |
| D | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0072522 | biological_process | purine-containing compound biosynthetic process |
| E | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005634 | cellular_component | nucleus |
| E | 0005739 | cellular_component | mitochondrion |
| E | 0005759 | cellular_component | mitochondrial matrix |
| E | 0006006 | biological_process | glucose metabolic process |
| E | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| E | 0006099 | biological_process | tricarboxylic acid cycle |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| E | 0032991 | cellular_component | protein-containing complex |
| E | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| E | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| E | 0046872 | molecular_function | metal ion binding |
| F | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005634 | cellular_component | nucleus |
| F | 0005739 | cellular_component | mitochondrion |
| F | 0005759 | cellular_component | mitochondrial matrix |
| F | 0006006 | biological_process | glucose metabolic process |
| F | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| F | 0006099 | biological_process | tricarboxylic acid cycle |
| F | 0009060 | biological_process | aerobic respiration |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0044272 | biological_process | sulfur compound biosynthetic process |
| F | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| F | 0046872 | molecular_function | metal ion binding |
| F | 0072522 | biological_process | purine-containing compound biosynthetic process |
| G | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0005634 | cellular_component | nucleus |
| G | 0005739 | cellular_component | mitochondrion |
| G | 0005759 | cellular_component | mitochondrial matrix |
| G | 0006006 | biological_process | glucose metabolic process |
| G | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| G | 0006099 | biological_process | tricarboxylic acid cycle |
| G | 0016491 | molecular_function | oxidoreductase activity |
| G | 0016624 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
| G | 0032991 | cellular_component | protein-containing complex |
| G | 0043231 | cellular_component | intracellular membrane-bounded organelle |
| G | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| G | 0046872 | molecular_function | metal ion binding |
| H | 0004739 | molecular_function | pyruvate dehydrogenase (acetyl-transferring) activity |
| H | 0005515 | molecular_function | protein binding |
| H | 0005634 | cellular_component | nucleus |
| H | 0005739 | cellular_component | mitochondrion |
| H | 0005759 | cellular_component | mitochondrial matrix |
| H | 0006006 | biological_process | glucose metabolic process |
| H | 0006086 | biological_process | pyruvate decarboxylation to acetyl-CoA |
| H | 0006099 | biological_process | tricarboxylic acid cycle |
| H | 0009060 | biological_process | aerobic respiration |
| H | 0016491 | molecular_function | oxidoreductase activity |
| H | 0044272 | biological_process | sulfur compound biosynthetic process |
| H | 0045254 | cellular_component | pyruvate dehydrogenase complex |
| H | 0046872 | molecular_function | metal ion binding |
| H | 0072522 | biological_process | purine-containing compound biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN C 1001 |
| Chain | Residue |
| C | ASP167 |
| C | ASN196 |
| C | TYR198 |
| C | TPP1002 |
| C | HOH2234 |
| site_id | AC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE TPP C 1002 |
| Chain | Residue |
| B | GLN88 |
| C | TYR89 |
| C | ARG90 |
| C | GLY136 |
| C | VAL138 |
| C | GLY166 |
| C | ASP167 |
| C | GLY168 |
| C | ALA169 |
| C | ASN196 |
| C | TYR198 |
| C | GLY199 |
| C | MET200 |
| C | HIS263 |
| C | MN1001 |
| C | HOH2200 |
| C | HOH2222 |
| C | HOH2234 |
| C | HOH2277 |
| C | HOH2489 |
| B | GLU28 |
| B | ILE57 |
| B | GLU59 |
| B | PHE85 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K B 1003 |
| Chain | Residue |
| B | ALA160 |
| B | ILE161 |
| B | ASP163 |
| B | HOH2133 |
| B | HOH2301 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 1004 |
| Chain | Residue |
| A | ASP167 |
| A | ASN196 |
| A | TYR198 |
| A | TPP1005 |
| A | HOH2039 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE TPP A 1005 |
| Chain | Residue |
| A | TYR89 |
| A | ARG90 |
| A | GLY136 |
| A | VAL138 |
| A | GLY166 |
| A | ASP167 |
| A | GLY168 |
| A | ALA169 |
| A | ASN196 |
| A | TYR198 |
| A | GLY199 |
| A | HIS263 |
| A | MN1004 |
| A | HOH2039 |
| A | HOH2043 |
| A | HOH2122 |
| A | HOH2149 |
| A | HOH2346 |
| D | GLU28 |
| D | ILE57 |
| D | GLU59 |
| D | PHE85 |
| D | GLN88 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K D 1006 |
| Chain | Residue |
| D | ARG75 |
| D | ALA160 |
| D | ILE161 |
| D | ASP163 |
| D | HOH2065 |
| D | HOH2159 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN G 1007 |
| Chain | Residue |
| G | ASP167 |
| G | ASN196 |
| G | TYR198 |
| G | TPP1008 |
| G | HOH2294 |
| site_id | AC8 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE TPP G 1008 |
| Chain | Residue |
| F | GLU28 |
| F | ILE57 |
| F | GLU59 |
| F | MET81 |
| F | PHE85 |
| F | GLN88 |
| G | TYR89 |
| G | ARG90 |
| G | GLY136 |
| G | VAL138 |
| G | GLY166 |
| G | ASP167 |
| G | GLY168 |
| G | ALA169 |
| G | ASN196 |
| G | TYR198 |
| G | GLY199 |
| G | MET200 |
| G | HIS263 |
| G | MN1007 |
| G | HOH2062 |
| G | HOH2249 |
| G | HOH2294 |
| G | HOH2355 |
| G | HOH2447 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K F 1009 |
| Chain | Residue |
| F | ALA160 |
| F | ILE161 |
| F | ASP163 |
| F | HOH2116 |
| F | HOH2636 |
| F | ARG75 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN E 1010 |
| Chain | Residue |
| E | ASP167 |
| E | ASN196 |
| E | TYR198 |
| E | TPP1011 |
| E | HOH2223 |
| site_id | BC2 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE TPP E 1011 |
| Chain | Residue |
| E | TYR89 |
| E | ARG90 |
| E | GLY136 |
| E | VAL138 |
| E | GLY166 |
| E | ASP167 |
| E | GLY168 |
| E | ALA169 |
| E | ASN196 |
| E | TYR198 |
| E | GLY199 |
| E | MET200 |
| E | HIS263 |
| E | MN1010 |
| E | HOH2130 |
| E | HOH2179 |
| E | HOH2223 |
| E | HOH2391 |
| E | HOH2500 |
| H | GLU28 |
| H | ILE57 |
| H | GLU59 |
| H | PHE85 |
| H | GLN88 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE K H 1012 |
| Chain | Residue |
| H | ALA160 |
| H | ILE161 |
| H | ASP163 |
| H | HOH2386 |
| H | HOH2397 |
| site_id | BC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1101 |
| Chain | Residue |
| A | LYS153 |
| A | TRP185 |
| A | LEU187 |
| A | HOH2650 |
| A | HOH2946 |
| A | HOH3205 |
| B | ASP49 |
| B | ILE53 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL C 1102 |
| Chain | Residue |
| C | LYS153 |
| C | TRP185 |
| C | HOH2477 |
| C | HOH2998 |
| C | HOH3876 |
| D | ASP49 |
| D | ILE53 |
| D | HOH2905 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL E 1103 |
| Chain | Residue |
| E | LYS153 |
| E | LEU187 |
| E | HOH2656 |
| E | HOH3689 |
| E | HOH3731 |
| F | ASP49 |
| F | ILE53 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL G 1104 |
| Chain | Residue |
| G | LYS153 |
| G | LEU187 |
| G | HOH3129 |
| G | HOH3379 |
| H | ASP49 |
| H | ILE53 |
| H | HOH2848 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"29970614","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"6CFO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17474719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29970614","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OZL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6CER","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NI4","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17474719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OZL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXH","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17474719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OZL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXF","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 12 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P35486","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by PDK1","evidences":[{"source":"PubMed","id":"11486000","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21406692","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P35486","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by PDK1, PDK2, PDK3 and PDK4","evidences":[{"source":"PubMed","id":"11486000","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17474719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P35486","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine; by PDK1, PDK2, PDK3 and PDK4","evidences":[{"source":"PubMed","id":"11486000","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P35486","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI13 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"19608861","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI14 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P35486","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI15 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI16 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17474719","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OZL","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI17 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17474719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OZL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI18 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3EXE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXI","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI19 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12651851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17474719","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19081061","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1NI4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2OZL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3EXE","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI20 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for interaction with DLAT","evidences":[{"source":"PubMed","id":"20160912","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI21 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q9D051","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI22 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"Q9D051","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| A | HIS263 |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| D | GLU59 | |
| D | HIS128 |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| F | GLU59 | |
| F | HIS128 |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| H | GLU59 | |
| H | HIS128 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| C | HIS263 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| E | HIS263 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| G | HIS263 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| B | GLU59 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| D | GLU59 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| F | GLU59 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| H | GLU59 |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dtw |
| Chain | Residue | Details |
| B | GLU59 | |
| B | HIS128 |
