3EX8
Complex structure of bacillus subtilis RibG reduction mechanism in riboflavin biosynthesis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008703 | molecular_function | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity |
| A | 0008835 | molecular_function | diaminohydroxyphosphoribosylaminopyrimidine deaminase activity |
| A | 0009231 | biological_process | riboflavin biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008703 | molecular_function | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity |
| B | 0008835 | molecular_function | diaminohydroxyphosphoribosylaminopyrimidine deaminase activity |
| B | 0009231 | biological_process | riboflavin biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050661 | molecular_function | NADP binding |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0008703 | molecular_function | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity |
| C | 0008835 | molecular_function | diaminohydroxyphosphoribosylaminopyrimidine deaminase activity |
| C | 0009231 | biological_process | riboflavin biosynthetic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0050661 | molecular_function | NADP binding |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0008703 | molecular_function | 5-amino-6-(5-phosphoribosylamino)uracil reductase activity |
| D | 0008835 | molecular_function | diaminohydroxyphosphoribosylaminopyrimidine deaminase activity |
| D | 0009231 | biological_process | riboflavin biosynthetic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 362 |
| Chain | Residue |
| A | HIS49 |
| A | CYS74 |
| A | CYS83 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 362 |
| Chain | Residue |
| B | HIS49 |
| B | GLU51 |
| B | CYS74 |
| B | CYS83 |
| B | HOH400 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 362 |
| Chain | Residue |
| C | CYS74 |
| C | CYS83 |
| C | HOH383 |
| C | HIS49 |
| site_id | AC4 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE AIF C 381 |
| Chain | Residue |
| C | LYS151 |
| C | ALA153 |
| C | SER167 |
| C | TRP169 |
| C | ILE170 |
| C | THR171 |
| C | ARG176 |
| C | ARG183 |
| C | THR195 |
| C | ASP199 |
| C | PRO201 |
| C | SER202 |
| C | LEU203 |
| C | ARG206 |
| C | GLU290 |
| C | HOH382 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN D 362 |
| Chain | Residue |
| D | HIS49 |
| D | CYS74 |
| D | CYS83 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 39 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEvhAIhmagahaegadiyvtle................PCshygktppCaelI |
| Chain | Residue | Details |
| A | HIS49-ILE87 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor => ECO:0000250 |
| Chain | Residue | Details |
| A | GLU51 | |
| B | GLU51 | |
| C | GLU51 | |
| D | GLU51 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS49 | |
| B | HIS49 | |
| B | CYS74 | |
| B | CYS83 | |
| B | ALA153 | |
| B | TRP169 | |
| B | THR195 | |
| B | ASP199 | |
| B | THR221 | |
| B | GLY292 | |
| C | HIS49 | |
| A | CYS74 | |
| C | CYS74 | |
| C | CYS83 | |
| C | ALA153 | |
| C | TRP169 | |
| C | THR195 | |
| C | ASP199 | |
| C | THR221 | |
| C | GLY292 | |
| D | HIS49 | |
| D | CYS74 | |
| A | CYS83 | |
| D | CYS83 | |
| D | ALA153 | |
| D | TRP169 | |
| D | THR195 | |
| D | ASP199 | |
| D | THR221 | |
| D | GLY292 | |
| A | ALA153 | |
| A | TRP169 | |
| A | THR195 | |
| A | ASP199 | |
| A | THR221 | |
| A | GLY292 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000250 |
| Chain | Residue | Details |
| A | SER167 | |
| B | GLU290 | |
| C | SER167 | |
| C | ARG183 | |
| C | LEU203 | |
| C | ARG206 | |
| C | GLU290 | |
| D | SER167 | |
| D | ARG183 | |
| D | LEU203 | |
| D | ARG206 | |
| A | ARG183 | |
| D | GLU290 | |
| A | LEU203 | |
| A | ARG206 | |
| A | GLU290 | |
| B | SER167 | |
| B | ARG183 | |
| B | LEU203 | |
| B | ARG206 |
