Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE K A 1 |
Chain | Residue |
A | SER32 |
A | THR35 |
A | EDO459 |
A | HOH534 |
A | HOH584 |
B | ASP100 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE K D 2 |
Chain | Residue |
C | TYR169 |
C | HOH505 |
D | SER32 |
D | THR35 |
A | HOH676 |
C | K5 |
C | ASP100 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE K C 3 |
Chain | Residue |
A | HOH702 |
A | HOH785 |
C | SER32 |
C | THR35 |
C | EDO459 |
D | ASP100 |
D | TYR169 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE K B 4 |
Chain | Residue |
A | ASP100 |
A | TYR169 |
A | HOH667 |
A | HOH681 |
B | EDO8 |
B | SER32 |
B | THR35 |
site_id | AC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE K C 5 |
site_id | AC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE CL B 6 |
Chain | Residue |
B | HIS378 |
B | GLU382 |
site_id | AC7 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO C 7 |
Chain | Residue |
A | HOH756 |
A | HOH800 |
C | ARG307 |
C | ARG314 |
C | GLN372 |
D | PRO80 |
D | GLU81 |
D | GLU137 |
site_id | AC8 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO B 8 |
Chain | Residue |
A | ILE99 |
A | ASP100 |
A | TYR169 |
B | K4 |
B | SER33 |
B | THR35 |
B | LEU37 |
B | EDO460 |
site_id | AC9 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 9 |
Chain | Residue |
A | EDO12 |
A | GLY102 |
A | SER105 |
A | HOH652 |
B | THR45 |
B | ARG49 |
B | TYR381 |
site_id | BC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 10 |
Chain | Residue |
B | GLN439 |
B | LYS443 |
B | PHE447 |
B | VAL449 |
site_id | BC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 11 |
Chain | Residue |
A | EDO12 |
A | ARG48 |
A | PHE51 |
A | ASN52 |
A | TYR103 |
A | HOH1074 |
site_id | BC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO A 12 |
Chain | Residue |
A | EDO11 |
A | GLY102 |
A | TYR103 |
A | HOH847 |
B | EDO9 |
B | EDO14 |
B | ARG48 |
site_id | BC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 13 |
Chain | Residue |
A | ARG48 |
A | EDO475 |
A | HOH1074 |
B | EDO14 |
B | GLY102 |
B | TYR103 |
site_id | BC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 14 |
Chain | Residue |
A | EDO12 |
A | EDO13 |
A | HOH847 |
B | ASN52 |
site_id | BC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO C 15 |
Chain | Residue |
C | EDO17 |
C | ARG48 |
C | EDO460 |
D | GLY102 |
D | TYR103 |
site_id | BC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO C 16 |
Chain | Residue |
C | THR35 |
C | EDO456 |
C | EDO459 |
D | ARG106 |
site_id | BC8 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 17 |
Chain | Residue |
C | EDO15 |
C | EDO460 |
D | PHE51 |
D | ASN52 |
D | HOH533 |
D | HOH594 |
site_id | BC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 18 |
Chain | Residue |
B | ASP330 |
B | CYS331 |
B | HOH596 |
B | GLY326 |
B | GLY328 |
B | PRO329 |
site_id | CC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO C 19 |
Chain | Residue |
C | GLY326 |
C | GLY328 |
C | PRO329 |
C | ASP330 |
C | HIS379 |
site_id | CC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 20 |
Chain | Residue |
A | GLU266 |
A | HIS268 |
A | GLU305 |
A | ASN308 |
A | HOH759 |
A | HOH875 |
site_id | CC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 21 |
Chain | Residue |
A | GLU225 |
A | HOH569 |
A | HOH826 |
site_id | CC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 452 |
Chain | Residue |
A | ASN61 |
A | LYS115 |
A | PHE119 |
A | LYS122 |
site_id | CC5 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO C 452 |
Chain | Residue |
C | ARG307 |
C | THR369 |
C | PRO370 |
C | ASP371 |
C | GLN372 |
D | GLY79 |
D | GLU81 |
site_id | CC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 453 |
Chain | Residue |
C | ARG106 |
C | GLU107 |
C | LEU110 |
C | SER174 |
C | GLU176 |
C | GLU177 |
site_id | CC7 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO D 452 |
Chain | Residue |
D | GLU266 |
D | HIS268 |
D | GLU305 |
D | ASN308 |
D | HOH500 |
D | HOH502 |
site_id | CC8 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 452 |
Chain | Residue |
B | TYR69 |
B | HIS70 |
B | TYR75 |
B | HOH571 |
site_id | CC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 453 |
Chain | Residue |
B | ARG319 |
B | HIS323 |
B | HOH620 |
site_id | DC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO D 453 |
Chain | Residue |
D | VAL367 |
D | TYR423 |
D | TRP429 |
D | EDO458 |
site_id | DC2 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO D 454 |
Chain | Residue |
D | GLU114 |
D | ARG183 |
site_id | DC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 453 |
Chain | Residue |
A | MSE71 |
A | TYR394 |
A | LYS406 |
A | HOH1024 |
B | EDO457 |
site_id | DC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 454 |
Chain | Residue |
A | GLU74 |
A | PRO76 |
A | ARG407 |
site_id | DC5 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO C 454 |
Chain | Residue |
C | ARG270 |
C | GLY273 |
site_id | DC6 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO B 454 |
Chain | Residue |
B | ARG197 |
B | ASN202 |
B | PRO242 |
B | ALA244 |
B | HOH482 |
site_id | DC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 455 |
Chain | Residue |
A | VAL292 |
A | VAL367 |
A | TYR423 |
A | EDO468 |
site_id | DC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO C 455 |
Chain | Residue |
A | HOH763 |
A | HOH800 |
C | ARG307 |
C | ASN308 |
D | PRO80 |
site_id | DC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 456 |
Chain | Residue |
A | SER36 |
A | LEU37 |
A | HIS378 |
A | TYR381 |
A | GLU382 |
site_id | EC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO C 456 |
Chain | Residue |
C | EDO16 |
C | SER36 |
C | LEU37 |
C | HIS378 |
C | TYR381 |
C | GLU382 |
site_id | EC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 457 |
Chain | Residue |
A | GLY326 |
A | GLY328 |
A | PRO329 |
A | ASP330 |
A | HOH1021 |
site_id | EC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO C 457 |
Chain | Residue |
A | HOH1005 |
C | ALA171 |
C | LYS178 |
C | HOH609 |
site_id | EC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 458 |
Chain | Residue |
A | GLU107 |
A | LEU110 |
A | SER174 |
A | HOH1033 |
site_id | EC5 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO C 458 |
Chain | Residue |
C | ASP100 |
C | THR425 |
C | LEU427 |
C | LYS430 |
D | HOH529 |
site_id | EC6 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 455 |
Chain | Residue |
B | ARG106 |
B | GLU107 |
B | LEU110 |
B | SER174 |
B | GLU176 |
B | HOH593 |
site_id | EC7 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO D 455 |
Chain | Residue |
D | GLU107 |
D | LEU110 |
D | SER174 |
D | GLU176 |
D | HOH668 |
site_id | EC8 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO A 459 |
Chain | Residue |
A | K1 |
A | SER33 |
A | THR35 |
A | LEU37 |
A | HOH1046 |
B | ILE99 |
B | ASP100 |
site_id | EC9 |
Number of Residues | 8 |
Details | BINDING SITE FOR RESIDUE EDO C 459 |
Chain | Residue |
C | K3 |
C | EDO16 |
C | SER33 |
C | THR35 |
C | LEU37 |
D | ILE99 |
D | ASP100 |
D | TYR169 |
site_id | FC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO C 460 |
Chain | Residue |
A | HOH829 |
C | EDO15 |
C | EDO17 |
C | ARG48 |
C | PHE51 |
C | ASN52 |
D | ARG48 |
site_id | FC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO D 456 |
Chain | Residue |
D | GLY326 |
D | GLY328 |
D | PRO329 |
D | ASP330 |
D | HIS379 |
site_id | FC3 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE EDO A 460 |
site_id | FC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 461 |
Chain | Residue |
A | GLU114 |
A | ARG183 |
A | HOH1075 |
site_id | FC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 462 |
Chain | Residue |
A | LYS295 |
A | ASP296 |
A | ASN448 |
site_id | FC6 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO C 461 |
Chain | Residue |
C | TYR381 |
C | GLY384 |
D | SER105 |
site_id | FC7 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO B 456 |
Chain | Residue |
A | HOH675 |
B | GLU263 |
site_id | FC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO C 462 |
Chain | Residue |
C | ASP290 |
C | TRP429 |
C | LYS451 |
site_id | FC9 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 457 |
Chain | Residue |
A | MSE71 |
A | EDO453 |
B | GLU266 |
site_id | GC1 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 458 |
Chain | Residue |
A | PRO80 |
A | GLU81 |
A | GLU137 |
B | ARG307 |
B | ARG314 |
B | GLN372 |
B | HOH577 |
site_id | GC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 459 |
Chain | Residue |
A | GLY79 |
A | GLU81 |
B | ARG307 |
B | THR369 |
B | PRO370 |
B | ASP371 |
B | GLN372 |
site_id | GC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO D 457 |
Chain | Residue |
D | ASP39 |
D | ASP371 |
D | HIS378 |
site_id | GC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO D 458 |
Chain | Residue |
D | PHE303 |
D | EDO453 |
D | EDO460 |
site_id | GC5 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 463 |
Chain | Residue |
A | ASP402 |
A | TRP403 |
A | TYR404 |
A | EDO465 |
A | HOH787 |
B | LYS451 |
site_id | GC6 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE EDO A 464 |
Chain | Residue |
A | GLY200 |
A | HOH890 |
site_id | GC7 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 465 |
Chain | Residue |
A | ALA401 |
A | ASP402 |
A | EDO463 |
A | HOH921 |
site_id | GC8 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 466 |
Chain | Residue |
A | ASN308 |
A | LEU311 |
A | EDO467 |
site_id | GC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 467 |
Chain | Residue |
A | ASN304 |
A | ARG307 |
A | ASN308 |
A | EDO466 |
A | HOH1057 |
site_id | HC1 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 460 |
Chain | Residue |
B | EDO8 |
B | ALA34 |
B | THR35 |
site_id | HC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 468 |
Chain | Residue |
A | ARG307 |
A | VAL367 |
A | PRO370 |
A | EDO455 |
site_id | HC3 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO C 463 |
Chain | Residue |
C | PRO436 |
C | HOH501 |
C | HOH609 |
site_id | HC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 461 |
Chain | Residue |
A | GLU74 |
B | VAL367 |
B | HOH680 |
site_id | HC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO C 464 |
Chain | Residue |
C | ASP290 |
C | LYS430 |
C | LYS451 |
C | HOH492 |
site_id | HC6 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE EDO B 462 |
Chain | Residue |
A | HOH625 |
B | ALA276 |
B | GLY277 |
B | GLY347 |
B | LEU349 |
B | ASP352 |
B | HOH499 |
site_id | HC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO D 459 |
Chain | Residue |
D | MSE71 |
D | TYR391 |
D | HOH499 |
site_id | HC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO D 460 |
Chain | Residue |
D | VAL292 |
D | GLY293 |
D | SER301 |
D | EDO458 |
D | HOH645 |
site_id | HC9 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 469 |
Chain | Residue |
A | ASP100 |
A | THR425 |
A | LEU427 |
A | LYS430 |
A | HOH961 |
site_id | IC1 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 470 |
Chain | Residue |
A | GLU67 |
A | TYR338 |
A | LEU409 |
A | HOH984 |
site_id | IC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO D 461 |
Chain | Residue |
D | ALA276 |
D | GLY277 |
D | GLY347 |
D | LEU349 |
D | ASP352 |
D | HOH586 |
site_id | IC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO A 471 |
Chain | Residue |
A | LYS122 |
A | ASP124 |
A | THR138 |
A | GLY139 |
A | HIS140 |
site_id | IC4 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 472 |
Chain | Residue |
A | ARG68 |
A | ILE82 |
A | TRP133 |
site_id | IC5 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO A 473 |
Chain | Residue |
A | GLN439 |
A | LYS443 |
A | PHE447 |
site_id | IC6 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE EDO B 463 |
Chain | Residue |
B | PHE54 |
B | GLY63 |
B | LEU64 |
B | ALA65 |
B | SER88 |
B | GLY91 |
B | ILE95 |
B | ARG112 |
B | ILE116 |
site_id | IC7 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE EDO A 474 |
Chain | Residue |
A | PHE54 |
A | GLY63 |
A | ALA65 |
A | SER88 |
A | GLY91 |
A | ILE92 |
A | ILE95 |
A | ARG112 |
A | ILE116 |
site_id | IC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO D 462 |
Chain | Residue |
C | GLY102 |
C | VAL104 |
D | THR45 |
D | ARG49 |
D | TYR381 |
site_id | IC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 475 |
Chain | Residue |
A | EDO13 |
A | THR45 |
A | ARG49 |
A | TYR381 |
A | EDO477 |
B | GLY102 |
site_id | JC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO B 464 |
Chain | Residue |
B | GLU67 |
B | HIS132 |
B | TYR343 |
B | ILE411 |
B | EDO465 |
B | HOH575 |
site_id | JC2 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 465 |
Chain | Residue |
B | GLU67 |
B | ARG68 |
B | TYR338 |
B | EDO464 |
site_id | JC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO A 476 |
Chain | Residue |
A | ASP290 |
A | MSE433 |
A | LYS451 |
A | HOH655 |
site_id | JC4 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO D 463 |
Chain | Residue |
C | VAL367 |
C | TYR423 |
C | TRP429 |
D | GLU74 |
site_id | JC5 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO D 464 |
Chain | Residue |
D | GLU67 |
D | ARG68 |
D | TYR338 |
D | HOH497 |
site_id | JC6 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE EDO B 466 |
Chain | Residue |
A | HOH831 |
B | HIS167 |
B | GLN168 |
B | PRO436 |
site_id | JC7 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE EDO B 467 |
Chain | Residue |
B | GLU225 |
B | TRP281 |
B | HOH515 |
site_id | JC8 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE EDO D 465 |
Chain | Residue |
A | HOH751 |
D | TRP206 |
D | GLU225 |
D | TRP281 |
D | HOH614 |
site_id | JC9 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE EDO A 477 |
Chain | Residue |
A | ARG49 |
A | PHE388 |
A | GLY389 |
A | PRO390 |
A | EDO475 |
A | HOH946 |