3EF5

Structure of the RNA pyrophosphohydrolase BdRppH in complex with dGTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005525	molecular_function	GTP binding
A	0006260	biological_process	DNA replication
A	0006281	biological_process	DNA repair
A	0008413	molecular_function	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
A	0016787	molecular_function	hydrolase activity
A	0035539	molecular_function	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
A	0042802	molecular_function	identical protein binding
A	0044715	molecular_function	8-oxo-dGDP phosphatase activity
A	0044716	molecular_function	8-oxo-GDP phosphatase activity
A	0046872	molecular_function	metal ion binding
B	0005525	molecular_function	GTP binding
B	0006260	biological_process	DNA replication
B	0006281	biological_process	DNA repair
B	0008413	molecular_function	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
B	0016787	molecular_function	hydrolase activity
B	0035539	molecular_function	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
B	0042802	molecular_function	identical protein binding
B	0044715	molecular_function	8-oxo-dGDP phosphatase activity
B	0044716	molecular_function	8-oxo-GDP phosphatase activity
B	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE DGT A3800

Chain	Residue
A	VAL24
A	ASN136
A	HOH3818
A	HOH3819
A	ARG40
A	PHE52
A	GLY54
A	GLY55
A	LYS56
A	ILE97
A	ILE99
A	PRO133

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site_id	AC2
Number of Residues	12
Details	BINDING SITE FOR RESIDUE DGT B3801

Chain	Residue
B	VAL24
B	ARG40
B	GLU51
B	PHE52
B	GLY54
B	GLY55
B	LYS56
B	ILE97
B	ILE99
B	PRO133
B	ASN136
B	HOH176

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Functional Information from PROSITE/UniProt

site_id	PS00893
Number of Residues	22
Details	NUDIX_BOX Nudix box signature. GkiengEtpeeALaRELnEElG

Chain	Residue	Details
A	GLY55-GLY76

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