3EE6
Crystal Structure Analysis of Tripeptidyl peptidase -I
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008236 | molecular_function | serine-type peptidase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Charge relay system => ECO:0000269|PubMed:19038966, ECO:0000269|PubMed:19038967 |
| Chain | Residue | Details |
| A | GLU272 | |
| A | ASP276 | |
| B | GLU272 | |
| B | ASP276 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system => ECO:0000269|PubMed:19038966, ECO:0000269|PubMed:19038967, ECO:0000305|PubMed:11054422 |
| Chain | Residue | Details |
| A | SER475 | |
| B | SER475 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:19038966, ECO:0000269|PubMed:19038967 |
| Chain | Residue | Details |
| A | ASP517 | |
| B | ASP543 | |
| A | VAL518 | |
| A | GLY539 | |
| A | GLY541 | |
| A | ASP543 | |
| B | ASP517 | |
| B | VAL518 | |
| B | GLY539 | |
| B | GLY541 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19038966, ECO:0000269|PubMed:19038967, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN210 | |
| A | ASN313 | |
| B | ASN210 | |
| B | ASN313 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN222 | |
| B | ASN222 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19038966, ECO:0000269|PubMed:19038967 |
| Chain | Residue | Details |
| A | ASN286 | |
| B | ASN286 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12754519, ECO:0000269|PubMed:19038966, ECO:0000269|PubMed:19038967, ECO:0000269|PubMed:19159218 |
| Chain | Residue | Details |
| A | ASN443 | |
| B | ASN443 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nlu |
| Chain | Residue | Details |
| A | GLU272 | |
| A | SER475 | |
| A | ASP276 | |
| A | ASP360 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1nlu |
| Chain | Residue | Details |
| B | GLU272 | |
| B | SER475 | |
| B | ASP276 | |
| B | ASP360 |
