3ECM
Crystal structure of the unliganded PDE8A catalytic domain
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ZN A 1 |
| Chain | Residue |
| A | HIS560 |
| A | HIS596 |
| A | ASP597 |
| A | ASP726 |
| A | HOH820 |
| A | HOH821 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 2 |
| Chain | Residue |
| A | HOH823 |
| A | HOH824 |
| A | HOH825 |
| A | ASP597 |
| A | HOH820 |
| A | HOH822 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDVdHpGrtNsF |
| Chain | Residue | Details |
| A | HIS596-PHE607 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"O76083","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18983167","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3ECM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ECN","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
