3E9J

Structure of the charge-transfer intermediate of the transmembrane redox catalyst DsbB

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0003756	molecular_function	protein disulfide isomerase activity
B	0005515	molecular_function	protein binding
B	0015035	molecular_function	protein-disulfide reductase activity
B	0015036	molecular_function	disulfide oxidoreductase activity
B	0016491	molecular_function	oxidoreductase activity
B	0030288	cellular_component	outer membrane-bounded periplasmic space
B	0042597	cellular_component	periplasmic space
B	0071236	biological_process	cellular response to antibiotic
C	0005515	molecular_function	protein binding
C	0005886	cellular_component	plasma membrane
C	0006457	biological_process	protein folding
C	0009055	molecular_function	electron transfer activity
C	0009408	biological_process	response to heat
C	0015035	molecular_function	protein-disulfide reductase activity
C	0016020	cellular_component	membrane
C	0016491	molecular_function	oxidoreductase activity
C	0016672	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
C	0048039	molecular_function	ubiquinone binding
E	0003756	molecular_function	protein disulfide isomerase activity
E	0005515	molecular_function	protein binding
E	0015035	molecular_function	protein-disulfide reductase activity
E	0015036	molecular_function	disulfide oxidoreductase activity
E	0016491	molecular_function	oxidoreductase activity
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0042597	cellular_component	periplasmic space
E	0071236	biological_process	cellular response to antibiotic
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006457	biological_process	protein folding
F	0009055	molecular_function	electron transfer activity
F	0009408	biological_process	response to heat
F	0015035	molecular_function	protein-disulfide reductase activity
F	0016020	cellular_component	membrane
F	0016491	molecular_function	oxidoreductase activity
F	0016672	molecular_function	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor
F	0048039	molecular_function	ubiquinone binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE UQ1 C 501

Chain	Residue
C	LYS39
C	CYS41
C	CYS44
C	GLU47
C	ARG48
C	HIS91
C	MET142
C	LEU146

---

site_id	AC2
Number of Residues	9
Details	BINDING SITE FOR RESIDUE UQ1 F 501

Chain	Residue
F	PRO40
F	CYS41
F	CYS44
F	GLU47
F	ARG48
F	HIS91
F	MET142
F	LEU146
F	LYS39

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	260
Details	Domain: {"description":"Thioredoxin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00691","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	96
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	34
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	4
Details	M-CSA 734

Chain	Residue	Details
B	HIS41	electrofuge, electrophile, nucleofuge, nucleophile
B	ASP44	electrofuge, electrophile, nucleofuge, nucleophile
B	LYS48	electrostatic stabiliser
B	SER104	covalently attached, nucleofuge, nucleophile

---

site_id	MCSA2
Number of Residues	4
Details	M-CSA 734

Chain

Residue

Details

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