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3E7J

HeparinaseII H202A/Y257A double mutant complexed with a heparan sulfate tetrasaccharide substrate

Functional Information from GO Data
ChainGOidnamespacecontents
A0016829molecular_functionlyase activity
B0016829molecular_functionlyase activity
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsACT_SITE: ACT_SITE => ECO:0000305|PubMed:20404324
ChainResidueDetails
AALA202
AALA257
AHIS406
BALA202
BALA257
BHIS406

site_idSWS_FT_FI2
Number of Residues20
DetailsBINDING: BINDING => ECO:0000269|PubMed:20404324
ChainResidueDetails
AARG96
AGLY470
BARG96
BASP145
BARG148
BASP196
BGLU205
BARG261
BASP307
BASN405
BTYR429
AASP145
BGLY470
AARG148
AASP196
AGLU205
AARG261
AASP307
AASN405
ATYR429

site_idSWS_FT_FI3
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:16565082, ECO:0000269|PubMed:20404324
ChainResidueDetails
AHIS408
AASP425
AHIS451
BHIS408
BASP425
BHIS451

site_idSWS_FT_FI4
Number of Residues2
DetailsBINDING:
ChainResidueDetails
ATYR436
BTYR436

site_idSWS_FT_FI5
Number of Residues2
DetailsCARBOHYD: O-linked (Man...) threonine => ECO:0000269|PubMed:16565082, ECO:0000269|PubMed:20404324
ChainResidueDetails
ATHR134
BTHR134

226707

PDB entries from 2024-10-30

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