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3E7C

Glucocorticoid Receptor LBD bound to GSK866

Functional Information from PDB Data
site_idAC1
Number of Residues15
DetailsBINDING SITE FOR RESIDUE 866 A 1
ChainResidue
ALEU563
APHE623
AGLN642
AMET646
ATYR735
ACYS736
ALEU753
AASN564
AGLY567
AGLN570
ATRP600
AMET601
AMET604
AALA607
AARG611

site_idAC2
Number of Residues6
DetailsBINDING SITE FOR RESIDUE GOL A 778
ChainResidue
APRO541
AALA574
ATRP577
ALEU603
AALA607
ALYS667

site_idAC3
Number of Residues15
DetailsBINDING SITE FOR RESIDUE 866 B 2
ChainResidue
BLEU563
BASN564
BGLN570
BTRP600
BMET601
BMET604
BALA607
BARG611
BPHE623
BGLY638
BGLN642
BMET646
BTYR735
BCYS736
BTHR739

site_idAC4
Number of Residues2
DetailsBINDING SITE FOR RESIDUE GOL B 3
ChainResidue
BGLY698
BASN711

site_idAC5
Number of Residues5
DetailsBINDING SITE FOR RESIDUE GOL B 778
ChainResidue
BPRO541
BTRP577
BMET604
BALA607
BLYS667

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO) => ECO:0000269|PubMed:12144530
ChainResidueDetails
AASN707
BGLU705

229183

PDB entries from 2024-12-18

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