3DZ8
Crystal structure of human Rab3B GTPase bound with GDP
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE GDP A 201 |
| Chain | Residue |
| A | SER32 |
| A | SER165 |
| A | ALA166 |
| A | LYS167 |
| A | HOH511 |
| A | HOH520 |
| A | HOH522 |
| A | GLY34 |
| A | LYS35 |
| A | THR36 |
| A | SER37 |
| A | ASN135 |
| A | LYS136 |
| A | ASP138 |
| A | MET139 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE UNX A 501 |
| Chain | Residue |
| A | SER31 |
| A | ALA79 |
| A | HOH510 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE UNX A 502 |
| Chain | Residue |
| A | PHE15 |
| A | GLN16 |
| A | ALA43 |
| A | ASP44 |
| A | THR48 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 504 |
| Chain | Residue |
| A | ARG66 |
| A | ARG173 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE UNX A 505 |
| Chain | Residue |
| A | ASN169 |
| A | ARG173 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 13 |
| Details | Motif: {"description":"Switch 1","evidences":[{"source":"PubMed","id":"35871249","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8A4B","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Motif: {"description":"Switch 2","evidences":[{"source":"PubMed","id":"35871249","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8A4B","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35871249","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8A4B","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"35871249","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8A4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8A4C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PDB","id":"8A4B","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8A4C","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of human RAB3B GTPase bound with GDP.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"3DZ8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine; by LRRK2","evidences":[{"source":"PubMed","id":"29125462","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | GLN81 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | SER32 |
