3DSH

Crystal structure of dimeric interferon regulatory factor 5 (IRF-5) transactivation domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphoserine; by TBK1 => ECO:0000269|PubMed:22412986

Chain	Residue	Details
A	SER283

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:22412986

Chain	Residue	Details
A	SER291

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P56477

Chain	Residue	Details
A	SER421

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:18836453, ECO:0000269|PubMed:22412986

Chain	Residue	Details
A	SER425

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site_id	SWS_FT_FI5
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:18836453

Chain	Residue	Details
A	SER427
A	ASP430

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site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine; by IKKB => ECO:0000269|PubMed:18836453, ECO:0000269|PubMed:22412986, ECO:0000269|PubMed:25326418

Chain	Residue	Details
A	SER436

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site_id	SWS_FT_FI7
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:18824541

Chain	Residue	Details
A	LYS401
A	LYS402

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