3DSD
Crystal structure of P. furiosus Mre11-H85S bound to a branched DNA and manganese
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000729 | biological_process | DNA double-strand break processing |
| A | 0006302 | biological_process | double-strand break repair |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0000729 | biological_process | DNA double-strand break processing |
| B | 0006302 | biological_process | double-strand break repair |
| B | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN A 403 |
| Chain | Residue |
| A | ASP8 |
| A | HIS10 |
| A | ASP49 |
| A | HIS208 |
| A | MN404 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 404 |
| Chain | Residue |
| A | HIS206 |
| A | MN403 |
| A | ASP8 |
| A | ASP49 |
| A | ASN84 |
| A | HIS173 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 405 |
| Chain | Residue |
| B | ASP49 |
| B | ASN84 |
| B | HIS173 |
| B | HIS206 |
| B | MN406 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MN B 406 |
| Chain | Residue |
| B | ASP8 |
| B | HIS10 |
| B | ASP49 |
| B | HIS208 |
| B | MN405 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_02044","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11371344","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"15047855","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11371344","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15047855","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18854158","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23080121","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1II7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1S8E","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3DSD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4HD0","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
