Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 500 |
| Chain | Residue |
| A | ASP60 |
| A | HOH1013 |
| A | HOH1026 |
| A | HOH1032 |
| A | HOH1055 |
| A | HOH1062 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 501 |
| Chain | Residue |
| B | ARG141 |
| A | THR74 |
| A | ASN88 |
| A | HOH1176 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 502 |
| Chain | Residue |
| B | TRP106 |
| B | HOH1056 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 503 |
| Chain | Residue |
| B | THR174 |
| B | ASN188 |
| B | HOH1007 |
| site_id | AC5 |
| Number of Residues | 29 |
| Details | BINDING SITE FOR RESIDUE G05 B 401 |
| Chain | Residue |
| A | LEU23 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | GLY48 |
| A | GLY49 |
| A | ILE50 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | HOH1001 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASP129 |
| B | ASP130 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | VAL182 |
| B | ILE184 |
| B | HOH1010 |
| B | HOH1073 |
| B | HOH1142 |
| B | HOH1144 |
| B | HOH1190 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE199 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| A | THR26 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | THR126 | |
| B | ASP125 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| A | ASP25 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1a30 |
| Chain | Residue | Details |
| B | ASP125 | |
