3DH1
Crystal structure of human tRNA-specific adenosine-34 deaminase subunit ADAT2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| B | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| C | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| D | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | HIS71 |
| A | GLU73 |
| A | CYS107 |
| A | CYS110 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 201 |
| Chain | Residue |
| C | HIS71 |
| C | GLU73 |
| C | CYS107 |
| C | CYS110 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 201 |
| Chain | Residue |
| D | GLU73 |
| D | CYS107 |
| D | CYS110 |
| D | HIS71 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 201 |
| Chain | Residue |
| B | HIS71 |
| B | GLU73 |
| B | CYS107 |
| B | CYS110 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 44 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEmvAIdqvldwcrqsgkspsevfehtvlyvtve.....PCim......CaaaL |
| Chain | Residue | Details |
| A | HIS71-LEU114 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 500 |
| Details | Domain: {"description":"CMP/dCMP-type deaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2009","submissionDatabase":"PDB data bank","title":"Crystal structure of human tRNA-specific adenosine-34 deaminase subunit ADAT2.","authoringGroup":["Structural genomics consortium (SGC)"]}}]} |
| Chain | Residue | Details |
