Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3DDO

X-RAY Structure of the Uridine Phosphorylase from Salmonella Typhimurium in Complex with by Phosphate Ion at 1.5A Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004850	molecular_function	uridine phosphorylase activity
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0009116	biological_process	nucleoside metabolic process
A	0009164	biological_process	nucleoside catabolic process
A	0009166	biological_process	nucleotide catabolic process
A	0016757	molecular_function	glycosyltransferase activity
A	0016763	molecular_function	pentosyltransferase activity
A	0044206	biological_process	UMP salvage
B	0003824	molecular_function	catalytic activity
B	0004850	molecular_function	uridine phosphorylase activity
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0009116	biological_process	nucleoside metabolic process
B	0009164	biological_process	nucleoside catabolic process
B	0009166	biological_process	nucleotide catabolic process
B	0016757	molecular_function	glycosyltransferase activity
B	0016763	molecular_function	pentosyltransferase activity
B	0044206	biological_process	UMP salvage
C	0003824	molecular_function	catalytic activity
C	0004850	molecular_function	uridine phosphorylase activity
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0009116	biological_process	nucleoside metabolic process
C	0009164	biological_process	nucleoside catabolic process
C	0009166	biological_process	nucleotide catabolic process
C	0016757	molecular_function	glycosyltransferase activity
C	0016763	molecular_function	pentosyltransferase activity
C	0044206	biological_process	UMP salvage
D	0003824	molecular_function	catalytic activity
D	0004850	molecular_function	uridine phosphorylase activity
D	0005737	cellular_component	cytoplasm
D	0005829	cellular_component	cytosol
D	0009116	biological_process	nucleoside metabolic process
D	0009164	biological_process	nucleoside catabolic process
D	0009166	biological_process	nucleotide catabolic process
D	0016757	molecular_function	glycosyltransferase activity
D	0016763	molecular_function	pentosyltransferase activity
D	0044206	biological_process	UMP salvage
E	0003824	molecular_function	catalytic activity
E	0004850	molecular_function	uridine phosphorylase activity
E	0005737	cellular_component	cytoplasm
E	0005829	cellular_component	cytosol
E	0009116	biological_process	nucleoside metabolic process
E	0009164	biological_process	nucleoside catabolic process
E	0009166	biological_process	nucleotide catabolic process
E	0016757	molecular_function	glycosyltransferase activity
E	0016763	molecular_function	pentosyltransferase activity
E	0044206	biological_process	UMP salvage
F	0003824	molecular_function	catalytic activity
F	0004850	molecular_function	uridine phosphorylase activity
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0009116	biological_process	nucleoside metabolic process
F	0009164	biological_process	nucleoside catabolic process
F	0009166	biological_process	nucleotide catabolic process
F	0016757	molecular_function	glycosyltransferase activity
F	0016763	molecular_function	pentosyltransferase activity
F	0044206	biological_process	UMP salvage

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PO4 F 1

Chain	Residue
A	ARG1048
F	GLY6026
F	ARG6091
F	ILE6092
F	GLY6093
F	THR6094

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 B 2

Chain	Residue
B	ILE2092
B	GLY2093
B	THR2094
D	ARG4048
B	GLY2026
B	ARG2030
B	ARG2091

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 D 3

Chain	Residue
B	ARG2048
D	GLY4026
D	ARG4030
D	ARG4091
D	ILE4092
D	GLY4093
D	THR4094

site_id	AC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A 4

Chain	Residue
A	GLY1026
A	ARG1030
A	ARG1091
A	ILE1092
A	GLY1093
A	THR1094
F	ARG6048

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PO4 C 5

Chain	Residue
C	GLY3026
C	ARG3091
C	ILE3092
C	GLY3093
C	THR3094

Functional Information from PROSITE/UniProt

site_id	PS01232
Number of Residues	16
Details	PNP_UDP_1 Purine and other phosphorylases family 1 signature. StGIGgPStSIaveEL

Chain	Residue	Details
A	SER1066-LEU1081

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
A	ARG1223
A	GLU1080
A	HIS1008

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
B	ARG2223
B	GLU2080
B	HIS2008

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
C	GLU3080
C	HIS3008
C	ARG3223

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
D	HIS4008
D	GLU4080
D	ARG4223

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
E	GLU5080
E	ARG5223
E	HIS5008

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1t0u

Chain	Residue	Details
F	HIS6008
F	GLU6080
F	ARG6223

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)