3DC8
Crystal structure of dihydropyrimidinase from Sinorhizobium meliloti
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| A | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| A | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016810 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
| B | 0016812 | molecular_function | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0055086 | biological_process | nucleobase-containing small molecule metabolic process |
| B | 0072527 | biological_process | pyrimidine-containing compound metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN A 501 |
| Chain | Residue |
| A | HIS180 |
| A | HIS236 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN A 502 |
| Chain | Residue |
| A | HIS56 |
| A | HIS58 |
| A | ASP313 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ZN B 501 |
| Chain | Residue |
| B | HIS180 |
| B | HIS236 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ZN B 502 |
| Chain | Residue |
| B | ASP313 |
| B | HIS56 |
| B | HIS58 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 503 |
| Chain | Residue |
| B | TYR47 |
| B | MET358 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ACT A 503 |
| Chain | Residue |
| A | ASN144 |
| A | GLY174 |
| A | ALA175 |
| A | LEU176 |
| A | ILE372 |
| A | PRO454 |
| A | PRO456 |
| A | SER459 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 504 |
| Chain | Residue |
| A | ASP296 |
| A | TRP299 |
| A | ARG355 |
| B | GLY253 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 505 |
| Chain | Residue |
| A | ALA303 |
| A | GLY354 |
| A | ARG355 |
| B | GLY253 |
| B | ARG255 |
| B | ALA461 |
| B | LEU462 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 506 |
| Chain | Residue |
| A | GLY253 |
| A | ARG255 |
| A | ALA461 |
| A | LEU462 |
| A | TRP465 |
| B | ALA303 |
| B | GLY354 |
| B | ARG355 |
| site_id | BC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL B 504 |
| Chain | Residue |
| A | LYS252 |
| A | GLY253 |
| B | ASP296 |
| B | TRP299 |
| B | ALA300 |
| B | ARG355 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| A | ASP313 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j79 |
| Chain | Residue | Details |
| B | ASP313 |
