3D5K

Crystal structure of the OprM channel in a non-symmetrical space group

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009279	cellular_component	cell outer membrane
A	0015297	molecular_function	antiporter activity
A	0015562	molecular_function	efflux transmembrane transporter activity
A	0016020	cellular_component	membrane
A	0022857	molecular_function	transmembrane transporter activity
A	0046677	biological_process	response to antibiotic
A	0055085	biological_process	transmembrane transport
A	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
A	1990281	cellular_component	efflux pump complex
B	0009279	cellular_component	cell outer membrane
B	0015297	molecular_function	antiporter activity
B	0015562	molecular_function	efflux transmembrane transporter activity
B	0016020	cellular_component	membrane
B	0022857	molecular_function	transmembrane transporter activity
B	0046677	biological_process	response to antibiotic
B	0055085	biological_process	transmembrane transport
B	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
B	1990281	cellular_component	efflux pump complex
C	0009279	cellular_component	cell outer membrane
C	0015297	molecular_function	antiporter activity
C	0015562	molecular_function	efflux transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0022857	molecular_function	transmembrane transporter activity
C	0046677	biological_process	response to antibiotic
C	0055085	biological_process	transmembrane transport
C	0140330	biological_process	xenobiotic detoxification by transmembrane export across the cell outer membrane
C	1990281	cellular_component	efflux pump complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 475

Chain	Residue
A	GLN367
A	ASP371
C	GLN229

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 476

Chain	Residue
A	TRP40
A	GLN154
A	TRP450

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 475

Chain	Residue
B	ARG432
B	ARG194
B	LEU256
B	LEU257

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site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA B 476

Chain	Residue
B	ALA228
B	ASN232
C	TYR24

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA B 477

Chain	Residue
B	ARG45
B	ASP46
B	LEU256

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site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE NA B 478

Chain	Residue
B	ALA66
B	THR146
B	GLN150
B	HOH513

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA B 479

Chain	Residue
B	TRP40
B	GLN154
B	TRP450

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site_id	AC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA B 480

Chain	Residue
B	TYR185
B	GLN418
B	HOH544

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site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 475

Chain	Residue
C	GLY29
C	GLY263
C	HOH478

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site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 476

Chain	Residue
C	ARG272
C	ASP274
C	ALA361

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