Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 34 |
| Details | BINDING SITE FOR RESIDUE ROC A 201 |
| Chain | Residue |
| A | ARG8 |
| A | VAL50 |
| A | THR80 |
| A | PRO81 |
| A | VAL82 |
| A | ILE84 |
| A | GOL801 |
| A | HOH1004 |
| A | HOH1005 |
| A | HOH1068 |
| A | HOH1162 |
| A | ASP25 |
| B | ARG8 |
| B | ASP25 |
| B | GLY27 |
| B | ASP29 |
| B | ASP30 |
| B | ILE47 |
| B | GLY48 |
| B | GLY49 |
| B | VAL50 |
| B | THR80 |
| A | GLY27 |
| B | PRO81 |
| B | ILE84 |
| B | HOH1192 |
| B | HOH1209 |
| B | HOH1238 |
| A | ALA28 |
| A | ASP29 |
| A | ASP30 |
| A | VAL32 |
| A | GLY48 |
| A | GLY49 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 501 |
| Chain | Residue |
| A | ASP60 |
| A | HOH1078 |
| A | HOH1103 |
| A | HOH1135 |
| A | HOH1156 |
| A | HOH1235 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY A 601 |
| Chain | Residue |
| A | MET46 |
| A | GOL801 |
| B | GLN61 |
| B | HOH1006 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 801 |
| Chain | Residue |
| A | ILE47 |
| A | GLY48 |
| A | ROC201 |
| A | ACY601 |
| A | HOH1049 |
| A | HOH1097 |
| B | PO4701 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PO4 B 701 |
| Chain | Residue |
| A | GOL801 |
| B | ARG8 |
| B | HOH1163 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
| Chain | Residue | Details |
| A | ALA22-ILE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP25 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE99 | |
