3CW2
Crystal structure of the intact archaeal translation initiation factor 2 from Sulfolobus solfataricus .
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0001731 | biological_process | formation of translation preinitiation complex |
| A | 0003743 | molecular_function | translation initiation factor activity |
| A | 0003746 | molecular_function | translation elongation factor activity |
| A | 0003924 | molecular_function | GTPase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005525 | molecular_function | GTP binding |
| A | 0006414 | biological_process | translational elongation |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0001731 | biological_process | formation of translation preinitiation complex |
| B | 0003743 | molecular_function | translation initiation factor activity |
| B | 0003746 | molecular_function | translation elongation factor activity |
| B | 0003924 | molecular_function | GTPase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005525 | molecular_function | GTP binding |
| B | 0006414 | biological_process | translational elongation |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0003743 | molecular_function | translation initiation factor activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006413 | biological_process | translational initiation |
| C | 0043022 | molecular_function | ribosome binding |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0003743 | molecular_function | translation initiation factor activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0006413 | biological_process | translational initiation |
| D | 0043022 | molecular_function | ribosome binding |
| E | 0000049 | molecular_function | tRNA binding |
| E | 0001731 | biological_process | formation of translation preinitiation complex |
| E | 0003743 | molecular_function | translation initiation factor activity |
| E | 0003746 | molecular_function | translation elongation factor activity |
| E | 0003924 | molecular_function | GTPase activity |
| E | 0005515 | molecular_function | protein binding |
| E | 0005525 | molecular_function | GTP binding |
| E | 0006414 | biological_process | translational elongation |
| F | 0000049 | molecular_function | tRNA binding |
| F | 0001731 | biological_process | formation of translation preinitiation complex |
| F | 0003743 | molecular_function | translation initiation factor activity |
| F | 0003746 | molecular_function | translation elongation factor activity |
| F | 0003924 | molecular_function | GTPase activity |
| F | 0005515 | molecular_function | protein binding |
| F | 0005525 | molecular_function | GTP binding |
| F | 0006414 | biological_process | translational elongation |
| G | 0003676 | molecular_function | nucleic acid binding |
| G | 0003723 | molecular_function | RNA binding |
| G | 0003743 | molecular_function | translation initiation factor activity |
| G | 0005515 | molecular_function | protein binding |
| G | 0006413 | biological_process | translational initiation |
| G | 0043022 | molecular_function | ribosome binding |
| H | 0003676 | molecular_function | nucleic acid binding |
| H | 0003723 | molecular_function | RNA binding |
| H | 0003743 | molecular_function | translation initiation factor activity |
| H | 0005515 | molecular_function | protein binding |
| H | 0006413 | biological_process | translational initiation |
| H | 0043022 | molecular_function | ribosome binding |
| K | 0003743 | molecular_function | translation initiation factor activity |
| K | 0006413 | biological_process | translational initiation |
| L | 0003743 | molecular_function | translation initiation factor activity |
| L | 0006413 | biological_process | translational initiation |
| M | 0003743 | molecular_function | translation initiation factor activity |
| M | 0006413 | biological_process | translational initiation |
| N | 0003743 | molecular_function | translation initiation factor activity |
| N | 0006413 | biological_process | translational initiation |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 597 |
| Details | Domain: {"description":"tr-type G","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 28 |
| Details | Region: {"description":"G1","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Region: {"description":"G2","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Region: {"description":"G3","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 12 |
| Details | Region: {"description":"G4","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Region: {"description":"G5","evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 40 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25690901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RCY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4RD1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 7 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"25690901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4RD1","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16407071","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"25690901","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AHO","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"Q8U082","evidenceCode":"ECO:0000250"},{"source":"HAMAP-Rule","id":"MF_00119","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 284 |
| Details | Domain: {"description":"S1 motif","evidences":[{"source":"HAMAP-Rule","id":"MF_00231","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | ASP19 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | ASP19 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| E | ASP19 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| F | ASP19 |
| site_id | CSA5 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| A | HIS97 |
| site_id | CSA6 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| B | HIS97 |
| site_id | CSA7 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| E | HIS97 |
| site_id | CSA8 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ksj |
| Chain | Residue | Details |
| F | HIS97 |
