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3CVV

Drosophila melanogaster (6-4) photolyase bound to ds DNA with a T-T (6-4) photolesion and F0 cofactor

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0003677molecular_functionDNA binding
A0003904molecular_functiondeoxyribodipyrimidine photo-lyase activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0032922biological_processcircadian regulation of gene expression
A0043153biological_processentrainment of circadian clock by photoperiod
A0071949molecular_functionFAD binding
Functional Information from PDB Data
site_idAC1
Number of Residues27
DetailsBINDING SITE FOR RESIDUE FAD A 521
ChainResidue
APHE244
AARG303
ATYR306
ATRP362
AHIS365
AARG368
AHIS369
APHE391
ALEU395
AASP397
AGLN398
ALYS246
AASP399
ALEU402
AASN403
AASN406
ATRP407
AHOH581
AHOH662
C64T8
ATHR258
ATHR259
AVAL260
ALEU261
ASER262
ALEU265
AGLN299

site_idAC2
Number of Residues18
DetailsBINDING SITE FOR RESIDUE FO1 A 522
ChainResidue
AARG13
APHE44
AILE45
ALEU46
AASP47
AARG60
AASP110
AGLU112
ATYR114
ASER115
AARG118
ALYS266
AGLN398
AHOH533
AHOH570
AHOH584
AHOH702
AHOH886

site_idAC3
Number of Residues6
DetailsBINDING SITE FOR RESIDUE EDO A 523
ChainResidue
ATRP458
ALYS459
AARG479
AGLU484
AHOH642
DHOH475

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO A 524
ChainResidue
ALYS189
AHIS437
ALYS441
AHOH907

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE EDO C 16
ChainResidue
CDG10
CHOH51
DDG6
DDC7

site_idAC6
Number of Residues5
DetailsBINDING SITE FOR RESIDUE EDO D 16
ChainResidue
AGLN418
ATYR419
APHE420
DDA9
DDC10

Catalytic Information from CSA
site_idCSA1
Number of Residues3
DetailsAnnotated By Reference To The Literature 1dnp
ChainResidueDetails
ATRP384
ATRP407
ATRP330

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PDB entries from 2024-11-06

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