Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004769 | molecular_function | steroid Delta-isomerase activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008202 | biological_process | steroid metabolic process |
| A | 0008203 | biological_process | cholesterol metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016995 | molecular_function | cholesterol oxidase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 37 |
| Details | BINDING SITE FOR RESIDUE FAD A 510 |
| Chain | Residue |
| A | GLY18 |
| A | GLY111 |
| A | GLY114 |
| A | GLY115 |
| A | ASN119 |
| A | GLY120 |
| A | GLY121 |
| A | MET122 |
| A | ILE218 |
| A | HIS248 |
| A | VAL250 |
| A | GLY20 |
| A | ALA288 |
| A | ALA289 |
| A | GLY290 |
| A | TYR446 |
| A | HIS447 |
| A | ASP474 |
| A | GLY475 |
| A | ASN485 |
| A | PRO486 |
| A | PHE487 |
| A | TYR21 |
| A | HOH517 |
| A | HOH518 |
| A | HOH524 |
| A | HOH530 |
| A | HOH533 |
| A | HOH535 |
| A | HOH573 |
| A | HOH600 |
| A | GLY22 |
| A | GLU41 |
| A | MET42 |
| A | TYR107 |
| A | GLY109 |
| A | ARG110 |
Functional Information from PROSITE/UniProt
| site_id | PS00623 |
| Number of Residues | 24 |
| Details | GMC_OXRED_1 GMC oxidoreductases signature 1. GRgVGGGSlVNggmAvtPkrnyfE |
| Chain | Residue | Details |
| A | GLY109-GLU132 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"8218217","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"8218217","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1COY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3COX","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1coy |
| Chain | Residue | Details |
| A | ASN485 | |
| A | GLU361 | |
| A | HIS447 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1coy |
| Chain | Residue | Details |
| A | ASN485 | |
| A | HIS447 | |
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 354 |
| Chain | Residue | Details |
| A | GLU361 | proton acceptor, proton donor |
| A | HIS447 | electrostatic stabiliser, hydrogen bond donor, proton acceptor, proton donor |
| A | ASN485 | activator, electrostatic stabiliser, increase acidity, increase basicity |
