3CO7
Crystal Structure of FoxO1 DBD Bound to DBE2 DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0003700 | molecular_function | DNA-binding transcription factor activity |
| C | 0006355 | biological_process | regulation of DNA-templated transcription |
| C | 0043565 | molecular_function | sequence-specific DNA binding |
| F | 0003700 | molecular_function | DNA-binding transcription factor activity |
| F | 0006355 | biological_process | regulation of DNA-templated transcription |
| F | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PROSITE/UniProt
| site_id | PS00658 |
| Number of Residues | 7 |
| Details | FORK_HEAD_2 Fork head domain signature 2. WKNSIRH |
| Chain | Residue | Details |
| C | TRP209-HIS215 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 152 |
| Details | DNA binding: {"description":"Fork-head","evidences":[{"source":"PROSITE-ProRule","id":"PRU00089","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Region: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Site: {"description":"DNA-binding","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine; by STK4/MST1","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19221179","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21245099","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"Phosphoserine; by STK4/MST1","evidences":[{"source":"PubMed","id":"18786403","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
