3CLD
Ligand binding domain of the glucocorticoid receptor complexed with fluticazone furoate
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GW6 A 1 |
| Chain | Residue |
| A | MET560 |
| A | MET639 |
| A | GLN642 |
| A | CYS643 |
| A | LEU732 |
| A | TYR735 |
| A | CYS736 |
| A | THR739 |
| A | PHE749 |
| A | LEU563 |
| A | ASN564 |
| A | GLY567 |
| A | GLN570 |
| A | MET604 |
| A | ALA605 |
| A | ARG611 |
| A | PHE623 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE GW6 B 2 |
| Chain | Residue |
| B | MET560 |
| B | LEU563 |
| B | ASN564 |
| B | GLY567 |
| B | GLN570 |
| B | MET601 |
| B | MET604 |
| B | ALA605 |
| B | ARG611 |
| B | PHE623 |
| B | MET639 |
| B | GLN642 |
| B | LEU732 |
| B | TYR735 |
| B | CYS736 |
| B | THR739 |
| B | PHE749 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO)","evidences":[{"source":"PubMed","id":"12144530","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 3"} |
| Chain | Residue | Details |
