3CKK

Crystal structure of human methyltransferase-like protein 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006400	biological_process	tRNA modification
A	0008176	molecular_function	tRNA (guanine(46)-N7)-methyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE SAM A 301

Chain	Residue
A	GLY54
A	MET112
A	LEU130
A	PHE131
A	ASP133
A	THR208
A	GLU210
A	HOH304
A	HOH328
A	HOH388
A	HOH488
A	CYS55
A	GLY56
A	GLU77
A	ILE78
A	ARG79
A	SER109
A	ASN110
A	ALA111

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 302

Chain	Residue
A	GLY54
A	MET112
A	PRO132
A	ASP133
A	HOH434

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Region: {"description":"Alpha6 helix","evidences":[{"source":"PubMed","id":"36599985","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PubMed","id":"36599982","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"36599985","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36599982","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"APR-2008","submissionDatabase":"PDB data bank","title":"Crystal structure of human methyltransferase-like protein 1.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"3CKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"8D9L","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"36599985","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8CTH","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"APR-2008","submissionDatabase":"PDB data bank","title":"Crystal structure of human methyltransferase-like protein 1.","authoringGroup":["Structural genomics consortium (SGC)"]}},{"source":"PDB","id":"3CKK","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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