Functional Information from GO Data
| Chain | GOid | namespace | contents |
| X | 0006508 | biological_process | proteolysis |
| X | 0008234 | molecular_function | cysteine-type peptidase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE K X 1 |
| Chain | Residue |
| X | GLY756 |
| X | ASP757 |
| X | GLU778 |
| X | 2HP830 |
| X | HOH876 |
| X | HOH919 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 2HP X 829 |
| Chain | Residue |
| X | SER596 |
| X | ASP761 |
| X | HIS762 |
| X | HOH892 |
| X | HOH904 |
| X | HOH905 |
| X | HOH937 |
| X | HOH980 |
| X | HOH986 |
| X | GLN590 |
| X | ASP594 |
| X | THR595 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 2HP X 830 |
| Chain | Residue |
| X | K1 |
| X | CYS755 |
| X | GLY756 |
| X | GLU778 |
| X | CYS809 |
| X | HIS810 |
| X | PHE811 |
| X | HOH919 |
| X | HOH921 |
| X | HOH974 |
Functional Information from PROSITE/UniProt
| site_id | PS00639 |
| Number of Residues | 11 |
| Details | THIOL_PROTEASE_HIS Eukaryotic thiol (cysteine) proteases histidine active site. ADHAVNIVGYG |
| Chain | Residue | Details |
| X | ALA760-GLY770 | |
| site_id | PS00640 |
| Number of Residues | 20 |
| Details | THIOL_PROTEASE_ASN Eukaryotic thiol (cysteine) proteases asparagine active site. YWIvRNSWgpyWGdeGYFkV |
| Chain | Residue | Details |
| X | TYR782-VAL801 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10089","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10090","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Ancestral active site","evidences":[{"source":"PubMed","id":"19591843","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"25599609","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 9pap |
| Chain | Residue | Details |
| X | HIS762 | |
| X | GLN590 | |
| X | ASN787 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 9pap |
| Chain | Residue | Details |
| X | HIS762 | |
| X | GLN590 | |
| X | ASN787 | |
| X | SER596 | |
