3CFS
Structural basis of the interaction of RbAp46/RbAp48 with histone H4
Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0000118 | cellular_component | histone deacetylase complex |
B | 0000122 | biological_process | negative regulation of transcription by RNA polymerase II |
B | 0000781 | cellular_component | chromosome, telomeric region |
B | 0003723 | molecular_function | RNA binding |
B | 0005515 | molecular_function | protein binding |
B | 0005634 | cellular_component | nucleus |
B | 0005654 | cellular_component | nucleoplasm |
B | 0005829 | cellular_component | cytosol |
B | 0006260 | biological_process | DNA replication |
B | 0006325 | biological_process | chromatin organization |
B | 0006338 | biological_process | chromatin remodeling |
B | 0006355 | biological_process | regulation of DNA-templated transcription |
B | 0007420 | biological_process | brain development |
B | 0016581 | cellular_component | NuRD complex |
B | 0016589 | cellular_component | NURF complex |
B | 0030308 | biological_process | negative regulation of cell growth |
B | 0030336 | biological_process | negative regulation of cell migration |
B | 0030512 | biological_process | negative regulation of transforming growth factor beta receptor signaling pathway |
B | 0035098 | cellular_component | ESC/E(Z) complex |
B | 0042393 | molecular_function | histone binding |
B | 0042659 | biological_process | regulation of cell fate specification |
B | 0045892 | biological_process | negative regulation of DNA-templated transcription |
B | 0045893 | biological_process | positive regulation of DNA-templated transcription |
B | 0048545 | biological_process | response to steroid hormone |
B | 0070370 | biological_process | cellular heat acclimation |
B | 0070822 | cellular_component | Sin3-type complex |
B | 1902455 | biological_process | negative regulation of stem cell population maintenance |
B | 1902459 | biological_process | positive regulation of stem cell population maintenance |
B | 1904949 | cellular_component | ATPase complex |
B | 2000736 | biological_process | regulation of stem cell differentiation |
E | 0046982 | molecular_function | protein heterodimerization activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE ARS B 412 |
Chain | Residue |
B | CYS116 |
Functional Information from PROSITE/UniProt
site_id | PS00678 |
Number of Residues | 15 |
Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSAsdDhTVCLWDI |
Chain | Residue | Details |
B | LEU192-ILE206 | |
B | LEU288-LEU302 | |
B | LEU332-LEU346 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000269|PubMed:22389435 |
Chain | Residue | Details |
E | LYS31 |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in UFM1); alternate => ECO:0000269|PubMed:30886146 |
Chain | Residue | Details |
E | LYS31 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: N6-acetyllysine; alternate => ECO:0007744|PubMed:19608861 |
Chain | Residue | Details |
B | LYS4 |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
B | THR10 |
site_id | SWS_FT_FI5 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
Chain | Residue | Details |
B | SER95 |
site_id | SWS_FT_FI6 |
Number of Residues | 1 |
Details | MOD_RES: N6-acetyllysine => ECO:0000250|UniProtKB:Q60973 |
Chain | Residue | Details |
B | LYS119 |
site_id | SWS_FT_FI7 |
Number of Residues | 1 |
Details | MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:Q60973 |
Chain | Residue | Details |
B | LYS159 |
site_id | SWS_FT_FI8 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
B | SER354 |
site_id | SWS_FT_FI9 |
Number of Residues | 1 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate |
Chain | Residue | Details |
B | LYS4 |
site_id | SWS_FT_FI10 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733 |
Chain | Residue | Details |
B | LYS159 |
site_id | SWS_FT_FI11 |
Number of Residues | 2 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
Chain | Residue | Details |
B | LYS101 | |
B | LYS155 |