3CF4
Structure of the CODH component of the M. barkeri ACDS complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006084 | biological_process | acetyl-CoA metabolic process |
| A | 0015948 | biological_process | methanogenesis |
| A | 0016151 | molecular_function | nickel cation binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0018492 | molecular_function | carbon-monoxide dehydrogenase (acceptor) activity |
| A | 0019385 | biological_process | methanogenesis, from acetate |
| A | 0042542 | biological_process | response to hydrogen peroxide |
| A | 0043885 | molecular_function | carbon-monoxide dehydrogenase (ferredoxin) activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050418 | molecular_function | hydroxylamine reductase activity |
| A | 0051536 | molecular_function | iron-sulfur cluster binding |
| A | 0051539 | molecular_function | 4 iron, 4 sulfur cluster binding |
| G | 0015948 | biological_process | methanogenesis |
| G | 0019385 | biological_process | methanogenesis, from acetate |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SF4 A 809 |
| Chain | Residue |
| A | CYS73 |
| A | GLN75 |
| A | CYS77 |
| A | CYS77 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SF4 A 810 |
| Chain | Residue |
| A | CYS84 |
| A | GLY92 |
| A | CYS94 |
| A | ARG104 |
| A | ALA184 |
| A | CYS76 |
| A | TYR78 |
| A | CYS79 |
| A | TYR81 |
| A | GLY82 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FE A 808 |
| Chain | Residue |
| A | HIS250 |
| A | CYS278 |
| A | CYS587 |
| A | WCC811 |
| A | HOH827 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE WCC A 811 |
| Chain | Residue |
| A | HIS250 |
| A | CYS277 |
| A | CYS323 |
| A | GLY522 |
| A | CYS523 |
| A | PRO524 |
| A | CYS552 |
| A | CYS587 |
| A | PHE634 |
| A | SER635 |
| A | LYS637 |
| A | FE808 |
| A | CMO812 |
| A | HOH827 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CMO A 812 |
| Chain | Residue |
| A | HIS117 |
| A | CYS587 |
| A | LYS637 |
| A | ILE641 |
| A | WCC811 |
| A | HOH827 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 A 813 |
| Chain | Residue |
| A | CYS427 |
| A | PRO428 |
| A | ILE433 |
| A | CYS455 |
| A | ILE456 |
| A | CYS458 |
| A | ARG459 |
| A | CYS461 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SF4 A 814 |
| Chain | Residue |
| A | CYS417 |
| A | ALA418 |
| A | ASP419 |
| A | CYS420 |
| A | GLY421 |
| A | CYS423 |
| A | MET437 |
| A | CYS465 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY A 815 |
| Chain | Residue |
| A | ARG91 |
| A | GLU331 |
| A | LYS334 |
| A | ARG459 |
| site_id | AC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY A 816 |
| Chain | Residue |
| A | THR406 |
| A | ASP407 |
| A | LYS477 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACY A 817 |
| Chain | Residue |
| A | ARG571 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 818 |
| Chain | Residue |
| A | MET708 |
| A | LYS711 |
| A | TRP730 |
| A | HIS734 |
| A | HOH951 |
| site_id | BC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 819 |
| Chain | Residue |
| A | GLU430 |
| A | HOH1017 |
| A | HOH1117 |
| G | LYS117 |
| G | ARG141 |
| site_id | BC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACY A 820 |
| Chain | Residue |
| A | ARG353 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY A 821 |
| Chain | Residue |
| A | PRO67 |
| A | ILE69 |
| A | LYS99 |
| A | HOH1216 |
| G | ALA127 |
| G | PHE131 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACY A 822 |
| Chain | Residue |
| A | LYS735 |
| A | THR760 |
| A | HOH1047 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACY A 823 |
| Chain | Residue |
| A | LEU108 |
| A | ARG109 |
| A | THR112 |
| A | VAL182 |
| A | GLN636 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACY A 824 |
| Chain | Residue |
| A | ASP290 |
| A | ARG291 |
| A | ARG292 |
| A | ARG607 |
| A | GLN796 |
| A | HOH1027 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 825 |
| Chain | Residue |
| A | HOH1159 |
| A | ARG607 |
| A | ARG623 |
| A | GLN796 |
| A | PRO797 |
| A | HOH999 |
| site_id | CC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL A 826 |
| Chain | Residue |
| A | MET259 |
| A | LEU283 |
| A | TYR286 |
| A | GLU288 |
| A | PRO293 |
| A | PRO294 |
| A | TYR295 |
| A | ALA296 |
| A | HOH929 |
| A | HOH959 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACY G 171 |
| Chain | Residue |
| A | THR669 |
| A | GLU744 |
| A | HOH1177 |
| G | TRP99 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL G 172 |
| Chain | Residue |
| A | LEU424 |
| A | LEU425 |
| A | HOH1017 |
| G | LYS118 |
| G | ARG141 |
| G | GLY142 |
| G | ASN153 |
| G | HOH216 |
| G | HOH247 |
| site_id | CC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG G 173 |
| Chain | Residue |
| G | LEU134 |
| G | THR136 |
| G | ASN146 |
| G | THR148 |
| G | HOH259 |
Functional Information from PROSITE/UniProt
| site_id | PS00198 |
| Number of Residues | 12 |
| Details | 4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CaDCGaCLlACP |
| Chain | Residue | Details |
| A | CYS417-PRO428 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01137, ECO:0000269|PubMed:18621675 |
| Chain | Residue | Details |
| A | CYS73 | |
| A | CYS77 | |
| A | CYS323 | |
| A | CYS523 | |
| A | CYS552 | |
| A | CYS587 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01137, ECO:0000269|PubMed:18621675, ECO:0007744|PDB:3CF4 |
| Chain | Residue | Details |
| A | CYS76 | |
| A | CYS458 | |
| A | CYS461 | |
| A | CYS465 | |
| A | CYS79 | |
| A | CYS84 | |
| A | CYS94 | |
| A | CYS417 | |
| A | CYS420 | |
| A | CYS423 | |
| A | CYS427 | |
| A | CYS455 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:18621675 |
| Chain | Residue | Details |
| A | HIS117 | |
| A | HIS250 | |
| A | CYS278 |
