Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3CF4

Structure of the CODH component of the M. barkeri ACDS complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004601	molecular_function	peroxidase activity
A	0005506	molecular_function	iron ion binding
A	0006084	biological_process	acetyl-CoA metabolic process
A	0015948	biological_process	methanogenesis
A	0016151	molecular_function	nickel cation binding
A	0016491	molecular_function	oxidoreductase activity
A	0019385	biological_process	methanogenesis, from acetate
A	0042542	biological_process	response to hydrogen peroxide
A	0043885	molecular_function	anaerobic carbon-monoxide dehydrogenase activity
A	0046872	molecular_function	metal ion binding
A	0050418	molecular_function	hydroxylamine reductase activity
A	0051536	molecular_function	iron-sulfur cluster binding
A	0051539	molecular_function	4 iron, 4 sulfur cluster binding
A	0098869	biological_process	cellular oxidant detoxification
G	0015948	biological_process	methanogenesis
G	0019385	biological_process	methanogenesis, from acetate

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SF4 A 809

Chain	Residue
A	CYS73
A	GLN75
A	CYS77
A	CYS77

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SF4 A 810

Chain	Residue
A	CYS84
A	GLY92
A	CYS94
A	ARG104
A	ALA184
A	CYS76
A	TYR78
A	CYS79
A	TYR81
A	GLY82

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE FE A 808

Chain	Residue
A	HIS250
A	CYS278
A	CYS587
A	WCC811
A	HOH827

site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE WCC A 811

Chain	Residue
A	HIS250
A	CYS277
A	CYS323
A	GLY522
A	CYS523
A	PRO524
A	CYS552
A	CYS587
A	PHE634
A	SER635
A	LYS637
A	FE808
A	CMO812
A	HOH827

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CMO A 812

Chain	Residue
A	HIS117
A	CYS587
A	LYS637
A	ILE641
A	WCC811
A	HOH827

site_id	AC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SF4 A 813

Chain	Residue
A	CYS427
A	PRO428
A	ILE433
A	CYS455
A	ILE456
A	CYS458
A	ARG459
A	CYS461

site_id	AC7
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SF4 A 814

Chain	Residue
A	CYS417
A	ALA418
A	ASP419
A	CYS420
A	GLY421
A	CYS423
A	MET437
A	CYS465

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACY A 815

Chain	Residue
A	ARG91
A	GLU331
A	LYS334
A	ARG459

site_id	AC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACY A 816

Chain	Residue
A	THR406
A	ASP407
A	LYS477

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACY A 817

Chain	Residue
A	ARG571

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACY A 818

Chain	Residue
A	MET708
A	LYS711
A	TRP730
A	HIS734
A	HOH951

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACY A 819

Chain	Residue
A	GLU430
A	HOH1017
A	HOH1117
G	LYS117
G	ARG141

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE ACY A 820

Chain	Residue
A	ARG353

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACY A 821

Chain	Residue
A	PRO67
A	ILE69
A	LYS99
A	HOH1216
G	ALA127
G	PHE131

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ACY A 822

Chain	Residue
A	LYS735
A	THR760
A	HOH1047

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ACY A 823

Chain	Residue
A	LEU108
A	ARG109
A	THR112
A	VAL182
A	GLN636

site_id	BC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACY A 824

Chain	Residue
A	ASP290
A	ARG291
A	ARG292
A	ARG607
A	GLN796
A	HOH1027

site_id	BC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 825

Chain	Residue
A	HOH1159
A	ARG607
A	ARG623
A	GLN796
A	PRO797
A	HOH999

site_id	CC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL A 826

Chain	Residue
A	MET259
A	LEU283
A	TYR286
A	GLU288
A	PRO293
A	PRO294
A	TYR295
A	ALA296
A	HOH929
A	HOH959

site_id	CC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ACY G 171

Chain	Residue
A	THR669
A	GLU744
A	HOH1177
G	TRP99

site_id	CC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GOL G 172

Chain	Residue
A	LEU424
A	LEU425
A	HOH1017
G	LYS118
G	ARG141
G	GLY142
G	ASN153
G	HOH216
G	HOH247

site_id	CC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE PEG G 173

Chain	Residue
G	LEU134
G	THR136
G	ASN146
G	THR148
G	HOH259

Functional Information from PROSITE/UniProt

site_id	PS00198
Number of Residues	12
Details	4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CaDCGaCLlACP

Chain	Residue	Details
A	CYS417-PRO428

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	29
Details	Domain: {"description":"4Fe-4S ferredoxin-type 1","evidences":[{"source":"HAMAP-Rule","id":"MF_01137","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	29
Details	Domain: {"description":"4Fe-4S ferredoxin-type 2","evidences":[{"source":"HAMAP-Rule","id":"MF_01137","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01137","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18621675","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01137","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"18621675","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3CF4","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18621675","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)