3CB2

Crystal structure of human gamma-tubulin bound to GDP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000070	biological_process	mitotic sister chromatid segregation
A	0000166	molecular_function	nucleotide binding
A	0000212	biological_process	meiotic spindle organization
A	0000226	biological_process	microtubule cytoskeleton organization
A	0000242	cellular_component	pericentriolar material
A	0000278	biological_process	mitotic cell cycle
A	0000794	cellular_component	condensed nuclear chromosome
A	0000930	cellular_component	gamma-tubulin complex
A	0000931	cellular_component	gamma-tubulin ring complex
A	0005200	molecular_function	structural constituent of cytoskeleton
A	0005515	molecular_function	protein binding
A	0005525	molecular_function	GTP binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005813	cellular_component	centrosome
A	0005814	cellular_component	centriole
A	0005819	cellular_component	spindle
A	0005827	cellular_component	polar microtubule
A	0005829	cellular_component	cytosol
A	0005874	cellular_component	microtubule
A	0005876	cellular_component	spindle microtubule
A	0005881	cellular_component	cytoplasmic microtubule
A	0005929	cellular_component	cilium
A	0007017	biological_process	microtubule-based process
A	0007020	biological_process	microtubule nucleation
A	0007052	biological_process	mitotic spindle organization
A	0015630	cellular_component	microtubule cytoskeleton
A	0031122	biological_process	cytoplasmic microtubule organization
A	0031252	cellular_component	cell leading edge
A	0036064	cellular_component	ciliary basal body
A	0042802	molecular_function	identical protein binding
A	0045177	cellular_component	apical part of cell
A	0055037	cellular_component	recycling endosome
A	0097730	cellular_component	non-motile cilium
A	0140490	molecular_function	microtubule nucleator activity
A	1990498	cellular_component	mitotic spindle microtubule
B	0000070	biological_process	mitotic sister chromatid segregation
B	0000166	molecular_function	nucleotide binding
B	0000212	biological_process	meiotic spindle organization
B	0000226	biological_process	microtubule cytoskeleton organization
B	0000242	cellular_component	pericentriolar material
B	0000278	biological_process	mitotic cell cycle
B	0000794	cellular_component	condensed nuclear chromosome
B	0000930	cellular_component	gamma-tubulin complex
B	0000931	cellular_component	gamma-tubulin ring complex
B	0005200	molecular_function	structural constituent of cytoskeleton
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005813	cellular_component	centrosome
B	0005814	cellular_component	centriole
B	0005819	cellular_component	spindle
B	0005827	cellular_component	polar microtubule
B	0005829	cellular_component	cytosol
B	0005874	cellular_component	microtubule
B	0005876	cellular_component	spindle microtubule
B	0005881	cellular_component	cytoplasmic microtubule
B	0005929	cellular_component	cilium
B	0007017	biological_process	microtubule-based process
B	0007020	biological_process	microtubule nucleation
B	0007052	biological_process	mitotic spindle organization
B	0015630	cellular_component	microtubule cytoskeleton
B	0031122	biological_process	cytoplasmic microtubule organization
B	0031252	cellular_component	cell leading edge
B	0036064	cellular_component	ciliary basal body
B	0042802	molecular_function	identical protein binding
B	0045177	cellular_component	apical part of cell
B	0055037	cellular_component	recycling endosome
B	0097730	cellular_component	non-motile cilium
B	0140490	molecular_function	microtubule nucleator activity
B	1990498	cellular_component	mitotic spindle microtubule

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE GDP A 500

Chain	Residue
A	GLY11
A	GLY146
A	ASN207
A	PHE225
A	ILE228
A	ASN229
A	GLN12
A	CYS13
A	GLN16
A	ASN102
A	SER140
A	GLY143
A	GLY144
A	THR145

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site_id	AC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE GDP B 501

Chain	Residue
B	GLY11
B	GLN12
B	CYS13
B	GLN16
B	SER140
B	GLY143
B	GLY144
B	THR145
B	GLY146
B	PRO173
B	GLU177
B	ASN207
B	PHE225
B	ILE228
B	ASN229

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Functional Information from PROSITE/UniProt

site_id	PS00227
Number of Residues	7
Details	TUBULIN Tubulin subunits alpha, beta, and gamma signature. AGGTGSG

Chain	Residue	Details
A	ALA142-GLY148

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine; by BRSK1","evidences":[{"source":"UniProtKB","id":"P83887","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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