Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0015036 | molecular_function | disulfide oxidoreductase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0004601 | molecular_function | peroxidase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0015036 | molecular_function | disulfide oxidoreductase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0098869 | biological_process | cellular oxidant detoxification |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GSH A 289 |
| Chain | Residue |
| A | ILE25 |
| A | GLN151 |
| A | THR52 |
| A | ASN54 |
| A | ILE82 |
| A | GLN87 |
| A | LYS100 |
| A | ILE101 |
| A | GLU117 |
| A | SER118 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GSH A 290 |
| Chain | Residue |
| A | ASN26 |
| A | ASN54 |
| A | PRO155 |
| A | GLY158 |
| A | GLY159 |
| A | TRP215 |
| B | ARG178 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GSH B 289 |
| Chain | Residue |
| B | ILE25 |
| B | THR52 |
| B | ASN54 |
| B | GLN87 |
| B | LYS100 |
| B | ILE101 |
| B | GLU117 |
| B | SER118 |
| B | GLN151 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GSH B 290 |
| Chain | Residue |
| A | ARG178 |
| B | ASN26 |
| B | ASN54 |
| B | PRO155 |
| B | GLY158 |
| B | GLY159 |
| B | TRP215 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 174 |
| Details | Domain: {"description":"GST N-terminal"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 252 |
| Details | Domain: {"description":"GST C-terminal"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 56 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 40 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"21222452","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 6 |
| Details | Binding site: {} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | SER49 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | SER49 | |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | TYR48 | |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | TYR48 | |
