3C6W

Crystal structure of the ING5 PHD finger in complex with H3K4me3 peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 1

Chain	Residue
A	CYS189
A	CYS191
A	HIS213
A	CYS216

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 2

Chain	Residue
A	CYS202
A	CYS207
A	CYS229
A	CYS232

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 3

Chain	Residue
C	CYS191
C	HIS213
C	CYS216
C	CYS189

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 4

Chain	Residue
C	CYS202
C	CYS207
C	CYS229
C	CYS232

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Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	44
Details	ZF_PHD_1 Zinc finger PHD-type signature. Cl.Chqvsygem.....................................IgCdnpdCpiewFHfaCvdlttkpkgk...................................WfCprC

Chain	Residue	Details
A	CYS189-CYS232

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	98
Details	ZN_FING: PHD-type => ECO:0000255|PROSITE-ProRule:PRU00146

Chain	Residue	Details
A	PRO186-GLU235
C	PRO186-GLU235

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000269|PubMed:18623064, ECO:0007744|PDB:3C6W

Chain	Residue	Details
A	CYS189
C	CYS191
C	CYS202
C	CYS207
C	HIS213
C	CYS216
C	CYS229
C	CYS232
A	CYS191
A	CYS202
A	CYS207
A	HIS213
A	CYS216
A	CYS229
A	CYS232
C	CYS189

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	SITE: Histone H3K4me3 binding => ECO:0000269|PubMed:18623064, ECO:0007744|PDB:3C6W

Chain	Residue	Details
A	TYR188
A	MET199
A	ASP203
A	TRP211
C	TYR188
C	MET199
C	ASP203
C	TRP211

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