3C5Y
Crystal structure of a putative ribose 5-phosphate isomerase (saro_3514) from novosphingobium aromaticivorans dsm at 1.81 A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| E | 0005975 | biological_process | carbohydrate metabolic process |
| E | 0016853 | molecular_function | isomerase activity |
| E | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| F | 0005975 | biological_process | carbohydrate metabolic process |
| F | 0016853 | molecular_function | isomerase activity |
| F | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| G | 0005975 | biological_process | carbohydrate metabolic process |
| G | 0016853 | molecular_function | isomerase activity |
| G | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| H | 0005975 | biological_process | carbohydrate metabolic process |
| H | 0016853 | molecular_function | isomerase activity |
| H | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| I | 0005975 | biological_process | carbohydrate metabolic process |
| I | 0016853 | molecular_function | isomerase activity |
| I | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| J | 0005975 | biological_process | carbohydrate metabolic process |
| J | 0016853 | molecular_function | isomerase activity |
| J | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| K | 0005975 | biological_process | carbohydrate metabolic process |
| K | 0016853 | molecular_function | isomerase activity |
| K | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| L | 0005975 | biological_process | carbohydrate metabolic process |
| L | 0016853 | molecular_function | isomerase activity |
| L | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| M | 0005975 | biological_process | carbohydrate metabolic process |
| M | 0016853 | molecular_function | isomerase activity |
| M | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| N | 0005975 | biological_process | carbohydrate metabolic process |
| N | 0016853 | molecular_function | isomerase activity |
| N | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| O | 0005975 | biological_process | carbohydrate metabolic process |
| O | 0016853 | molecular_function | isomerase activity |
| O | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
| P | 0005975 | biological_process | carbohydrate metabolic process |
| P | 0016853 | molecular_function | isomerase activity |
| P | 0016861 | molecular_function | intramolecular oxidoreductase activity, interconverting aldoses and ketoses |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 F 213 |
| Chain | Residue |
| F | TYR195 |
| F | ARG208 |
| F | NO3214 |
| F | NO3215 |
| F | HOH434 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NO3 F 214 |
| Chain | Residue |
| F | PRO196 |
| F | NO3213 |
| F | HOH389 |
| F | HOH434 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO3 F 215 |
| Chain | Residue |
| F | ALA191 |
| F | TYR195 |
| F | ARG208 |
| F | NO3213 |
| F | HOH422 |
| F | HOH427 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NO3 F 216 |
| Chain | Residue |
| F | GLN-1 |
| F | GLY0 |
| F | MSE1 |
| F | GLY30 |
| F | LYS32 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE NO3 G 213 |
| Chain | Residue |
| G | TYR195 |
| G | ARG208 |
| G | NO3214 |
| G | HOH329 |
| G | HOH434 |
| J | TYR195 |
| J | PRO196 |
| J | ARG208 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE NO3 G 214 |
| Chain | Residue |
| G | ALA191 |
| G | TYR195 |
| G | ARG208 |
| G | NO3213 |
| G | HOH426 |
| G | HOH427 |
| J | ALA191 |
| J | TYR195 |
| J | ARG208 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NO3 I 213 |
| Chain | Residue |
| I | GLY0 |
| I | GLY30 |
| I | LYS32 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NO3 P 213 |
| Chain | Residue |
| O | TYR49 |
| P | ARG147 |
| P | ILE150 |
| P | MSE151 |
| P | ASN154 |
| P | HOH221 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 213 |
| Chain | Residue |
| A | PHE89 |
| A | ASN106 |
| A | ARG155 |
| A | LEU158 |
| A | ARG159 |
| A | HOH245 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 214 |
| Chain | Residue |
| A | ASP163 |
| A | CYS166 |
| A | HOH252 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 215 |
| Chain | Residue |
| A | LYS174 |
| A | THR175 |
| A | VAL176 |
| A | GLN178 |
| A | HOH356 |
| A | HOH383 |
| H | LYS174 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 216 |
| Chain | Residue |
| A | ASP168 |
| A | LEU170 |
| A | THR171 |
| A | LYS174 |
| A | HOH315 |
| A | HOH400 |
| H | THR175 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 217 |
| Chain | Residue |
| A | ARG147 |
| A | ILE150 |
| A | MSE151 |
| A | ASN154 |
| B | TYR49 |
| B | HOH250 |
| B | HOH278 |
| site_id | BC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 218 |
| Chain | Residue |
| A | ASN61 |
| A | SER62 |
| site_id | BC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 219 |
| Chain | Residue |
| A | LYS32 |
| A | VAL33 |
| A | LEU193 |
| A | HOH249 |
| A | HOH260 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 220 |
| Chain | Residue |
| A | ASP95 |
| A | ASN126 |
| A | HOH298 |
| C | ASP95 |
| D | LYS117 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 213 |
| Chain | Residue |
| A | HOH281 |
| B | PHE89 |
| B | ASN106 |
| B | ARG155 |
| B | LEU158 |
| B | ARG159 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 214 |
| Chain | Residue |
| B | PHE100 |
| B | LYS133 |
| B | HOH281 |
| D | ASP129 |
| site_id | CC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 215 |
| Chain | Residue |
| B | HOH327 |
| B | HOH355 |
| B | HOH398 |
| B | HOH419 |
| D | ILE94 |
| B | ASP95 |
| site_id | CC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 216 |
| Chain | Residue |
| B | ARG167 |
| B | THR171 |
| B | EDO217 |
| B | HOH280 |
| G | ARG167 |
| G | THR171 |
| G | HOH292 |
| site_id | CC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO B 217 |
| Chain | Residue |
| A | ARG167 |
| B | ARG167 |
| B | EDO216 |
| B | HOH297 |
| B | HOH401 |
| B | HOH421 |
| G | ARG167 |
| H | ARG167 |
| H | HOH369 |
| site_id | CC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 218 |
| Chain | Residue |
| B | ASP177 |
| B | GLN178 |
| B | HOH261 |
| B | HOH379 |
| G | HOH235 |
| J | EDO215 |
| site_id | CC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO C 213 |
| Chain | Residue |
| C | PHE89 |
| C | ASN106 |
| C | ARG155 |
| C | ARG159 |
| C | HOH301 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 214 |
| Chain | Residue |
| C | ILE94 |
| C | HOH253 |
| C | HOH259 |
| C | HOH270 |
| site_id | CC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO D 213 |
| Chain | Residue |
| C | HOH316 |
| D | ASN106 |
| D | ARG155 |
| D | ARG159 |
| site_id | CC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO D 214 |
| Chain | Residue |
| C | ARG167 |
| D | ARG167 |
| D | ASP168 |
| D | THR171 |
| E | HOH336 |
| F | ARG167 |
| site_id | CC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO E 213 |
| Chain | Residue |
| E | PHE89 |
| E | ASN106 |
| E | ARG155 |
| E | ARG159 |
| E | HOH249 |
| E | HOH420 |
| E | HOH442 |
| site_id | DC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO E 214 |
| Chain | Residue |
| E | PRO86 |
| E | LYS162 |
| E | ASP163 |
| E | CYS166 |
| E | HOH260 |
| E | HOH356 |
| site_id | DC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE EDO E 215 |
| Chain | Residue |
| E | ARG147 |
| E | ILE150 |
| E | MSE151 |
| E | ASN154 |
| E | HOH230 |
| E | HOH268 |
| F | TYR49 |
| F | EDO219 |
| F | HOH232 |
| site_id | DC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO E 216 |
| Chain | Residue |
| E | LYS14 |
| E | SER116 |
| E | PHE119 |
| site_id | DC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO E 217 |
| Chain | Residue |
| E | PRO144 |
| E | ARG145 |
| E | GLU146 |
| site_id | DC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO F 217 |
| Chain | Residue |
| F | PHE100 |
| F | LYS133 |
| H | LEU125 |
| H | HOH251 |
| site_id | DC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO F 218 |
| Chain | Residue |
| F | PHE89 |
| F | ASN106 |
| F | ARG155 |
| F | LEU158 |
| F | ARG159 |
| F | HOH241 |
| site_id | DC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO F 219 |
| Chain | Residue |
| E | ILE105 |
| E | MSE151 |
| E | EDO215 |
| F | SER10 |
| F | CSD72 |
| F | GLY73 |
| F | HOH257 |
| G | TRP121 |
| site_id | DC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO F 220 |
| Chain | Residue |
| F | SER10 |
| F | GLN11 |
| F | ALA12 |
| F | ALA13 |
| F | LYS14 |
| site_id | DC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO F 221 |
| Chain | Residue |
| F | PHE34 |
| F | GLU192 |
| F | ASN197 |
| F | HOH234 |
| F | HOH307 |
| F | HOH428 |
| site_id | EC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO F 222 |
| Chain | Residue |
| F | MSE51 |
| F | LEU180 |
| F | HOH416 |
| site_id | EC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO G 215 |
| Chain | Residue |
| G | PHE89 |
| G | ASN106 |
| G | ARG155 |
| G | ARG159 |
| G | HOH229 |
| site_id | EC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO G 216 |
| Chain | Residue |
| E | HOH322 |
| G | PHE100 |
| G | LYS133 |
| G | HOH402 |
| site_id | EC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO G 217 |
| Chain | Residue |
| F | TRP121 |
| G | SER10 |
| G | CSD72 |
| G | GLY73 |
| G | HOH413 |
| H | MSE151 |
| site_id | EC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO G 218 |
| Chain | Residue |
| E | ILE94 |
| E | ASN126 |
| E | HOH279 |
| G | ASP95 |
| G | HOH282 |
| G | HOH441 |
| site_id | EC6 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO G 219 |
| Chain | Residue |
| G | GLU192 |
| G | ASN197 |
| site_id | EC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO G 220 |
| Chain | Residue |
| E | LEU125 |
| E | HOH292 |
| G | HOH383 |
| site_id | EC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO G 221 |
| Chain | Residue |
| B | LYS174 |
| G | THR175 |
| G | VAL176 |
| G | ASP177 |
| G | HOH288 |
| site_id | EC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO H 213 |
| Chain | Residue |
| H | PHE89 |
| H | ASN106 |
| H | ARG155 |
| H | LEU158 |
| H | ARG159 |
| H | HOH276 |
| H | HOH363 |
| site_id | FC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO H 214 |
| Chain | Residue |
| H | PRO86 |
| H | ASP163 |
| H | CYS166 |
| H | HOH295 |
| site_id | FC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO H 215 |
| Chain | Residue |
| F | ILE94 |
| F | ASN126 |
| H | ASP95 |
| H | HOH315 |
| H | HOH343 |
| H | HOH347 |
| site_id | FC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO H 216 |
| Chain | Residue |
| E | TRP121 |
| G | ARG147 |
| H | GLU8 |
| H | SER10 |
| H | CSD72 |
| H | GLY73 |
| site_id | FC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO H 217 |
| Chain | Residue |
| H | ASP177 |
| H | GLN178 |
| H | ASP179 |
| H | HOH301 |
| H | HOH323 |
| H | HOH366 |
| site_id | FC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO H 218 |
| Chain | Residue |
| F | TYR143 |
| H | PHE119 |
| H | GLY120 |
| H | TRP121 |
| H | ALA122 |
| H | GLU124 |
| site_id | FC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO I 214 |
| Chain | Residue |
| I | PHE89 |
| I | ASN106 |
| I | ARG155 |
| I | LEU158 |
| I | ARG159 |
| I | HOH251 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO I 215 |
| Chain | Residue |
| I | PHE100 |
| I | LYS133 |
| I | HOH225 |
| I | HOH256 |
| L | ASP129 |
| site_id | FC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO I 216 |
| Chain | Residue |
| I | LYS117 |
| I | GLY118 |
| I | HOH323 |
| I | HOH398 |
| K | GLY118 |
| K | HOH364 |
| site_id | FC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO I 217 |
| Chain | Residue |
| I | LYS2 |
| I | PRO196 |
| I | ASN197 |
| I | HOH258 |
| I | HOH315 |
| site_id | GC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO J 213 |
| Chain | Residue |
| I | HOH292 |
| J | PHE89 |
| J | ASN106 |
| J | ARG155 |
| J | ARG159 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO J 214 |
| Chain | Residue |
| J | ASP168 |
| J | LEU170 |
| J | THR171 |
| J | LYS174 |
| O | ARG167 |
| site_id | GC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO J 215 |
| Chain | Residue |
| B | EDO218 |
| G | ASN205 |
| G | TYR206 |
| G | HOH232 |
| J | LYS189 |
| J | GLU192 |
| site_id | GC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO K 213 |
| Chain | Residue |
| K | PHE89 |
| K | ASN106 |
| K | ARG155 |
| K | ARG159 |
| K | HOH236 |
| site_id | GC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO K 214 |
| Chain | Residue |
| J | HOH329 |
| K | PHE100 |
| K | LYS133 |
| K | HOH315 |
| site_id | GC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO K 215 |
| Chain | Residue |
| J | ASN126 |
| K | ASP95 |
| K | HOH334 |
| K | HOH349 |
| site_id | GC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO L 213 |
| Chain | Residue |
| L | PHE89 |
| L | ASN106 |
| L | ARG155 |
| L | ARG159 |
| L | HOH220 |
| site_id | GC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO M 213 |
| Chain | Residue |
| M | PHE89 |
| M | ASN106 |
| M | ARG155 |
| M | LEU158 |
| M | ARG159 |
| M | HOH228 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO M 214 |
| Chain | Residue |
| M | LYS32 |
| M | VAL33 |
| M | PHE34 |
| M | EDO215 |
| M | HOH268 |
| site_id | HC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO M 215 |
| Chain | Residue |
| M | LYS32 |
| M | PHE34 |
| M | GLU192 |
| M | ASN197 |
| M | EDO214 |
| site_id | HC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO M 216 |
| Chain | Residue |
| L | THR175 |
| M | ASP168 |
| M | LEU170 |
| M | THR171 |
| M | LYS174 |
| site_id | HC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO N 213 |
| Chain | Residue |
| N | PHE89 |
| N | ASN106 |
| N | ARG155 |
| N | ARG159 |
| N | HOH227 |
| site_id | HC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO N 214 |
| Chain | Residue |
| N | PHE100 |
| N | LYS133 |
| N | HOH248 |
| N | HOH254 |
| O | LEU125 |
| O | ASP129 |
| site_id | HC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO N 215 |
| Chain | Residue |
| M | LYS117 |
| N | ASP95 |
| N | HOH297 |
| O | ILE94 |
| O | ASN126 |
| site_id | HC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO P 214 |
| Chain | Residue |
| P | PHE89 |
| P | ASN106 |
| P | ARG155 |
| P | LEU158 |
| P | ARG159 |
| P | HOH224 |
