3C20
Crystal Structure of Threonine-sensitive Aspartokinase from Methanococcus jannaschii with L-aspartate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004072 | molecular_function | aspartate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009088 | biological_process | threonine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0009090 | biological_process | homoserine biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004072 | molecular_function | aspartate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009088 | biological_process | threonine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0009090 | biological_process | homoserine biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ASP B 474 |
| Chain | Residue |
| B | SER40 |
| B | THR46 |
| B | GLU130 |
| B | ARG207 |
| B | GLY208 |
| B | GLY209 |
| B | SER210 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE ASP A 474 |
| Chain | Residue |
| A | GLU130 |
| A | PHE193 |
| A | ARG207 |
| A | GLY208 |
| A | GLY209 |
| A | SER210 |
| A | SER40 |
| A | THR46 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 475 |
| Chain | Residue |
| A | ALA417 |
| A | ILE420 |
| A | ALA421 |
| A | GLN440 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FMT B 475 |
| Chain | Residue |
| B | ALA417 |
| B | LYS418 |
| B | GLY419 |
| B | ILE420 |
| B | ALA421 |
Functional Information from PROSITE/UniProt
| site_id | PS00324 |
| Number of Residues | 9 |
| Details | ASPARTOKINASE Aspartokinase signature. VmKFGGTSV |
| Chain | Residue | Details |
| A | VAL4-VAL12 |
