3C02

X-ray structure of the aquaglyceroporin from Plasmodium falciparum

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006833	biological_process	water transport
A	0008519	molecular_function	ammonium channel activity
A	0009247	biological_process	glycolipid biosynthetic process
A	0015166	molecular_function	polyol transmembrane transporter activity
A	0015168	molecular_function	glycerol transmembrane transporter activity
A	0015204	molecular_function	urea transmembrane transporter activity
A	0015250	molecular_function	water channel activity
A	0015254	molecular_function	glycerol channel activity
A	0015267	molecular_function	channel activity
A	0015791	biological_process	polyol transmembrane transport
A	0015793	biological_process	glycerol transmembrane transport
A	0016020	cellular_component	membrane
A	0042802	molecular_function	identical protein binding
A	0051475	biological_process	glucosylglycerol transmembrane transport
A	0055085	biological_process	transmembrane transport
A	0071918	biological_process	urea transmembrane transport
A	0072488	biological_process	ammonium transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	63
Details	TOPO_DOM: Cytoplasmic => ECO:0000305

Chain	Residue	Details
A	MET1-ARG11
A	ALA67-LYS87
A	ASP157-SER171
A	ASP239-LEU258

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site_id	SWS_FT_FI2
Number of Residues	120
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	GLU12-ALA32
A	LEU46-GLY66
A	ILE88-GLY108
A	GLY136-VAL156
A	VAL172-LEU192
A	PHE218-TYR238

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site_id	SWS_FT_FI3
Number of Residues	62
Details	TOPO_DOM: Extracellular => ECO:0000305

Chain	Residue	Details
A	ASN33-LYS45
A	LEU109-THR135
A	ASN193-ASN217

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site_id	SWS_FT_FI4
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:18500352, ECO:0007744|PDB:3C02

Chain	Residue	Details
A	GLY66
A	ALA67
A	ASN70
A	SER127
A	GLY189
A	PHE190
A	ASN193
A	ARG196

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