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3BUM

Crystal structure of c-Cbl-TKB domain complexed with its binding motif in Sprouty2

Functional Information from GO Data
ChainGOidnamespacecontents
B0001784molecular_functionphosphotyrosine residue binding
B0004842molecular_functionubiquitin-protein transferase activity
B0005509molecular_functioncalcium ion binding
B0007166biological_processcell surface receptor signaling pathway
B0023051biological_processregulation of signaling
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues5
DetailsBINDING: BINDING => ECO:0007744|PDB:1B47, ECO:0007744|PDB:2CBL
ChainResidueDetails
BASP229
BTHR231
BASN233
BTYR235
BGLU240

site_idSWS_FT_FI2
Number of Residues1
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
BARG294

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PDB entries from 2024-07-24

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