3BU0

crystal structure of human ABH2 cross-linked to dsDNA with cofactors

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006281	biological_process	DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	BINDING SITE FOR RESIDUE AKG A 301

Chain	Residue
A	LEU157
A	ARG254
A	MN302
A	HOH405
A	HOH451
A	ASN159
A	TYR161
A	ILE168
A	HIS171
A	ASP173
A	HIS236
A	ARG248
A	ASN250

---

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MN A 302

Chain	Residue
A	HIS171
A	ASP173
A	HIS236
A	AKG301
A	HOH451

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	105
Details	Domain: {"description":"Fe2OG dioxygenase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00805","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18432238","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18432238","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22659876","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22659876","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---