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3BTS

Crystal structure of a ternary complex of the transcriptional repressor Gal80p (Gal80S0 [G301R]) and the acidic activation domain of Gal4p (aa 854-874) from Saccharomyces cerevisiae with NAD

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000166molecular_functionnucleotide binding
A0000431biological_processregulation of transcription from RNA polymerase II promoter by galactose
A0000435biological_processpositive regulation of transcription from RNA polymerase II promoter by galactose
A0003677molecular_functionDNA binding
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005667cellular_componenttranscription regulator complex
A0005737cellular_componentcytoplasm
A0006012biological_processgalactose metabolic process
A0017053cellular_componenttranscription repressor complex
A0019210molecular_functionkinase inhibitor activity
A0042326biological_processnegative regulation of phosphorylation
A0042802molecular_functionidentical protein binding
A0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0000166molecular_functionnucleotide binding
B0000431biological_processregulation of transcription from RNA polymerase II promoter by galactose
B0000435biological_processpositive regulation of transcription from RNA polymerase II promoter by galactose
B0003677molecular_functionDNA binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005667cellular_componenttranscription regulator complex
B0005737cellular_componentcytoplasm
B0006012biological_processgalactose metabolic process
B0017053cellular_componenttranscription repressor complex
B0019210molecular_functionkinase inhibitor activity
B0042326biological_processnegative regulation of phosphorylation
B0042802molecular_functionidentical protein binding
B0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
Functional Information from PDB Data
site_idAC1
Number of Residues14
DetailsBINDING SITE FOR RESIDUE NAD A 436
ChainResidue
AGLY24
AGLU122
ATRP123
AGLN151
AHIS213
EASP509
AASN26
AGLY30
ATRP31
APRO55
AALA93
AILE94
AGLN95
AHIS99

site_idAC2
Number of Residues15
DetailsBINDING SITE FOR RESIDUE NAD B 436
ChainResidue
BGLY24
BASN26
BLYS29
BGLY30
BTRP31
BPRO55
BALA93
BILE94
BGLN95
BSER98
BHIS99
BGLU122
BTRP123
BGLN151
BHIS213

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: N-acetylmethionine => ECO:0000269|PubMed:1985957
ChainResidueDetails
AMET1
BMET1

218853

PDB entries from 2024-04-24

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