3BSO

Norwalk Virus polymerase bound to cytidine 5'-triphosphate and primer-template RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0004386	molecular_function	helicase activity
A	0005524	molecular_function	ATP binding
A	0006351	biological_process	DNA-templated transcription
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 515

Chain	Residue
A	ARG30
A	LEU36
A	ARG52
A	SER427
A	HOH627
A	HOH630
A	HOH822

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site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL A 516

Chain	Residue
A	GLU260
A	GLN273
A	HOH669
A	ALA256
A	LEU259

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site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MN A 511

Chain	Residue
A	ASP242
A	ASP343
A	ASP344
A	CTP514
A	HOH658
P	G8

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 512

Chain	Residue
A	ASP242
A	TYR243
A	ASP343
A	CTP514

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MN A 513

Chain	Residue
A	ASP99
A	GLU205
A	HIS209
A	ASP289

---

site_id	AC6
Number of Residues	20
Details	BINDING SITE FOR RESIDUE CTP A 514

Chain	Residue
A	LYS166
A	ARG182
A	ASP242
A	TYR243
A	SER244
A	ARG245
A	TRP246
A	ASP247
A	SER300
A	THR305
A	ASN309
A	ASP343
A	MN511
A	MN512
A	HOH658
A	HOH722
A	HOH759
A	HOH840
P	G8
T	G2

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site_id	AC7
Number of Residues	10
Details	BINDING SITE FOR RESIDUE GOL P 9

Chain	Residue
A	PHE28
A	LEU169
A	ARG413
A	GLN414
A	TRP417
A	ARG419
A	HOH838
P	C5
P	G6
P	HOH21

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site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL T 10

Chain	Residue
A	LYS166
T	G2
T	C3
T	C4
T	HOH11
T	HOH32
T	HOH40

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