3BLW

Yeast Isocitrate Dehydrogenase with Citrate and AMP Bound in the Regulatory Subunits

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0003723	molecular_function	RNA binding
A	0003824	molecular_function	catalytic activity
A	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
A	0005515	molecular_function	protein binding
A	0005739	cellular_component	mitochondrion
A	0005758	cellular_component	mitochondrial intermembrane space
A	0005759	cellular_component	mitochondrial matrix
A	0005829	cellular_component	cytosol
A	0006099	biological_process	tricarboxylic acid cycle
A	0006102	biological_process	isocitrate metabolic process
A	0006537	biological_process	glutamate biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0042645	cellular_component	mitochondrial nucleoid
A	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
A	0046872	molecular_function	metal ion binding
A	0051287	molecular_function	NAD binding
B	0000287	molecular_function	magnesium ion binding
B	0003723	molecular_function	RNA binding
B	0003824	molecular_function	catalytic activity
B	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
B	0005515	molecular_function	protein binding
B	0005739	cellular_component	mitochondrion
B	0005759	cellular_component	mitochondrial matrix
B	0006099	biological_process	tricarboxylic acid cycle
B	0006102	biological_process	isocitrate metabolic process
B	0006537	biological_process	glutamate biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
B	0046872	molecular_function	metal ion binding
B	0051287	molecular_function	NAD binding
C	0000287	molecular_function	magnesium ion binding
C	0003723	molecular_function	RNA binding
C	0003824	molecular_function	catalytic activity
C	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
C	0005515	molecular_function	protein binding
C	0005739	cellular_component	mitochondrion
C	0005758	cellular_component	mitochondrial intermembrane space
C	0005759	cellular_component	mitochondrial matrix
C	0005829	cellular_component	cytosol
C	0006099	biological_process	tricarboxylic acid cycle
C	0006102	biological_process	isocitrate metabolic process
C	0006537	biological_process	glutamate biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0042645	cellular_component	mitochondrial nucleoid
C	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
C	0046872	molecular_function	metal ion binding
C	0051287	molecular_function	NAD binding
D	0000287	molecular_function	magnesium ion binding
D	0003723	molecular_function	RNA binding
D	0003824	molecular_function	catalytic activity
D	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
D	0005515	molecular_function	protein binding
D	0005739	cellular_component	mitochondrion
D	0005759	cellular_component	mitochondrial matrix
D	0006099	biological_process	tricarboxylic acid cycle
D	0006102	biological_process	isocitrate metabolic process
D	0006537	biological_process	glutamate biosynthetic process
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
D	0046872	molecular_function	metal ion binding
D	0051287	molecular_function	NAD binding
E	0000287	molecular_function	magnesium ion binding
E	0003723	molecular_function	RNA binding
E	0003824	molecular_function	catalytic activity
E	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
E	0005515	molecular_function	protein binding
E	0005739	cellular_component	mitochondrion
E	0005758	cellular_component	mitochondrial intermembrane space
E	0005759	cellular_component	mitochondrial matrix
E	0005829	cellular_component	cytosol
E	0006099	biological_process	tricarboxylic acid cycle
E	0006102	biological_process	isocitrate metabolic process
E	0006537	biological_process	glutamate biosynthetic process
E	0016491	molecular_function	oxidoreductase activity
E	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
E	0042645	cellular_component	mitochondrial nucleoid
E	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
E	0046872	molecular_function	metal ion binding
E	0051287	molecular_function	NAD binding
F	0000287	molecular_function	magnesium ion binding
F	0003723	molecular_function	RNA binding
F	0003824	molecular_function	catalytic activity
F	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
F	0005515	molecular_function	protein binding
F	0005739	cellular_component	mitochondrion
F	0005759	cellular_component	mitochondrial matrix
F	0006099	biological_process	tricarboxylic acid cycle
F	0006102	biological_process	isocitrate metabolic process
F	0006537	biological_process	glutamate biosynthetic process
F	0016491	molecular_function	oxidoreductase activity
F	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
F	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
F	0046872	molecular_function	metal ion binding
F	0051287	molecular_function	NAD binding
G	0000287	molecular_function	magnesium ion binding
G	0003723	molecular_function	RNA binding
G	0003824	molecular_function	catalytic activity
G	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
G	0005515	molecular_function	protein binding
G	0005739	cellular_component	mitochondrion
G	0005758	cellular_component	mitochondrial intermembrane space
G	0005759	cellular_component	mitochondrial matrix
G	0005829	cellular_component	cytosol
G	0006099	biological_process	tricarboxylic acid cycle
G	0006102	biological_process	isocitrate metabolic process
G	0006537	biological_process	glutamate biosynthetic process
G	0016491	molecular_function	oxidoreductase activity
G	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
G	0042645	cellular_component	mitochondrial nucleoid
G	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
G	0046872	molecular_function	metal ion binding
G	0051287	molecular_function	NAD binding
H	0000287	molecular_function	magnesium ion binding
H	0003723	molecular_function	RNA binding
H	0003824	molecular_function	catalytic activity
H	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
H	0005515	molecular_function	protein binding
H	0005739	cellular_component	mitochondrion
H	0005759	cellular_component	mitochondrial matrix
H	0006099	biological_process	tricarboxylic acid cycle
H	0006102	biological_process	isocitrate metabolic process
H	0006537	biological_process	glutamate biosynthetic process
H	0016491	molecular_function	oxidoreductase activity
H	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
H	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
H	0046872	molecular_function	metal ion binding
H	0051287	molecular_function	NAD binding
I	0000287	molecular_function	magnesium ion binding
I	0003723	molecular_function	RNA binding
I	0003824	molecular_function	catalytic activity
I	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005758	cellular_component	mitochondrial intermembrane space
I	0005759	cellular_component	mitochondrial matrix
I	0005829	cellular_component	cytosol
I	0006099	biological_process	tricarboxylic acid cycle
I	0006102	biological_process	isocitrate metabolic process
I	0006537	biological_process	glutamate biosynthetic process
I	0016491	molecular_function	oxidoreductase activity
I	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
I	0042645	cellular_component	mitochondrial nucleoid
I	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
I	0046872	molecular_function	metal ion binding
I	0051287	molecular_function	NAD binding
J	0000287	molecular_function	magnesium ion binding
J	0003723	molecular_function	RNA binding
J	0003824	molecular_function	catalytic activity
J	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
J	0005515	molecular_function	protein binding
J	0005739	cellular_component	mitochondrion
J	0005759	cellular_component	mitochondrial matrix
J	0006099	biological_process	tricarboxylic acid cycle
J	0006102	biological_process	isocitrate metabolic process
J	0006537	biological_process	glutamate biosynthetic process
J	0016491	molecular_function	oxidoreductase activity
J	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
J	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
J	0046872	molecular_function	metal ion binding
J	0051287	molecular_function	NAD binding
K	0000287	molecular_function	magnesium ion binding
K	0003723	molecular_function	RNA binding
K	0003824	molecular_function	catalytic activity
K	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
K	0005515	molecular_function	protein binding
K	0005739	cellular_component	mitochondrion
K	0005758	cellular_component	mitochondrial intermembrane space
K	0005759	cellular_component	mitochondrial matrix
K	0005829	cellular_component	cytosol
K	0006099	biological_process	tricarboxylic acid cycle
K	0006102	biological_process	isocitrate metabolic process
K	0006537	biological_process	glutamate biosynthetic process
K	0016491	molecular_function	oxidoreductase activity
K	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
K	0042645	cellular_component	mitochondrial nucleoid
K	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
K	0046872	molecular_function	metal ion binding
K	0051287	molecular_function	NAD binding
L	0000287	molecular_function	magnesium ion binding
L	0003723	molecular_function	RNA binding
L	0003824	molecular_function	catalytic activity
L	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
L	0005515	molecular_function	protein binding
L	0005739	cellular_component	mitochondrion
L	0005759	cellular_component	mitochondrial matrix
L	0006099	biological_process	tricarboxylic acid cycle
L	0006102	biological_process	isocitrate metabolic process
L	0006537	biological_process	glutamate biosynthetic process
L	0016491	molecular_function	oxidoreductase activity
L	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
L	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
L	0046872	molecular_function	metal ion binding
L	0051287	molecular_function	NAD binding
M	0000287	molecular_function	magnesium ion binding
M	0003723	molecular_function	RNA binding
M	0003824	molecular_function	catalytic activity
M	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
M	0005515	molecular_function	protein binding
M	0005739	cellular_component	mitochondrion
M	0005758	cellular_component	mitochondrial intermembrane space
M	0005759	cellular_component	mitochondrial matrix
M	0005829	cellular_component	cytosol
M	0006099	biological_process	tricarboxylic acid cycle
M	0006102	biological_process	isocitrate metabolic process
M	0006537	biological_process	glutamate biosynthetic process
M	0016491	molecular_function	oxidoreductase activity
M	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
M	0042645	cellular_component	mitochondrial nucleoid
M	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
M	0046872	molecular_function	metal ion binding
M	0051287	molecular_function	NAD binding
N	0000287	molecular_function	magnesium ion binding
N	0003723	molecular_function	RNA binding
N	0003824	molecular_function	catalytic activity
N	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
N	0005515	molecular_function	protein binding
N	0005739	cellular_component	mitochondrion
N	0005759	cellular_component	mitochondrial matrix
N	0006099	biological_process	tricarboxylic acid cycle
N	0006102	biological_process	isocitrate metabolic process
N	0006537	biological_process	glutamate biosynthetic process
N	0016491	molecular_function	oxidoreductase activity
N	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
N	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
N	0046872	molecular_function	metal ion binding
N	0051287	molecular_function	NAD binding
O	0000287	molecular_function	magnesium ion binding
O	0003723	molecular_function	RNA binding
O	0003824	molecular_function	catalytic activity
O	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
O	0005515	molecular_function	protein binding
O	0005739	cellular_component	mitochondrion
O	0005758	cellular_component	mitochondrial intermembrane space
O	0005759	cellular_component	mitochondrial matrix
O	0005829	cellular_component	cytosol
O	0006099	biological_process	tricarboxylic acid cycle
O	0006102	biological_process	isocitrate metabolic process
O	0006537	biological_process	glutamate biosynthetic process
O	0016491	molecular_function	oxidoreductase activity
O	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
O	0042645	cellular_component	mitochondrial nucleoid
O	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
O	0046872	molecular_function	metal ion binding
O	0051287	molecular_function	NAD binding
P	0000287	molecular_function	magnesium ion binding
P	0003723	molecular_function	RNA binding
P	0003824	molecular_function	catalytic activity
P	0004449	molecular_function	isocitrate dehydrogenase (NAD+) activity
P	0005515	molecular_function	protein binding
P	0005739	cellular_component	mitochondrion
P	0005759	cellular_component	mitochondrial matrix
P	0006099	biological_process	tricarboxylic acid cycle
P	0006102	biological_process	isocitrate metabolic process
P	0006537	biological_process	glutamate biosynthetic process
P	0016491	molecular_function	oxidoreductase activity
P	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
P	0045242	cellular_component	isocitrate dehydrogenase complex (NAD+)
P	0046872	molecular_function	metal ion binding
P	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC A 1001

Chain	Residue
A	THR83
B	LYS189
A	SER92
A	ASN94
A	VAL95
A	ARG98
A	ARG129
A	PHE136
A	THR241
A	ARG274

---

site_id	AC2
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC C 1002

Chain	Residue
C	THR83
C	SER92
C	ASN94
C	VAL95
C	ARG98
C	ARG129
C	PHE136
C	THR241
C	ARG274
D	LYS189

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC E 1003

Chain	Residue
E	THR83
E	SER92
E	ARG98
E	ARG129
E	PHE136
E	THR241
E	ARG274
F	LYS189
F	THR191
F	ASP222

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE FLC G 1004

Chain	Residue
G	THR83
G	SER92
G	VAL95
G	ARG98
G	ARG129
G	PHE136
G	THR241
G	ARG274
H	LYS189
H	THR191

---

site_id	AC5
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FLC I 1005

Chain	Residue
I	THR83
I	SER92
I	VAL95
I	ARG98
I	ARG129
I	PHE136
I	THR241
I	ARG274
J	LYS189

---

site_id	AC6
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FLC K 1006

Chain	Residue
K	THR83
K	SER92
K	ARG98
K	ARG129
K	PHE136
K	THR241
K	ARG274
L	LYS189
L	ASP222

---

site_id	AC7
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FLC M 1007

Chain	Residue
M	THR83
M	SER92
M	ASN94
M	VAL95
M	ARG98
M	PHE136
M	THR241
M	ARG274
N	LYS189

---

site_id	AC8
Number of Residues	9
Details	BINDING SITE FOR RESIDUE FLC O 1008

Chain	Residue
O	THR83
O	SER92
O	ASN94
O	ARG98
O	ARG129
O	PHE136
O	THR241
O	ARG274
P	LYS189

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE AMP A 2001

Chain	Residue
A	HIS275
A	GLY277
A	ALA286
A	ASN287
A	ASP328
B	ASN223

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE AMP C 2002

Chain	Residue
C	VAL28
C	ILE32
C	GLY255
C	HIS275
C	VAL276
C	GLY277
C	ASN287
D	ASN223

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE AMP E 2003

Chain	Residue
E	VAL28
E	HIS275
E	GLY277
E	ASN287
F	ASN223

---

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE AMP G 2004

Chain	Residue
G	ASN287
G	ASP328
H	ASN223
G	VAL28
G	HIS275
G	GLY277
G	ALA286

---

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE AMP I 2005

Chain	Residue
I	HIS275
I	GLY277
I	ALA286
I	ASN287
I	ASP328
J	ASN223

---

site_id	BC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE AMP K 2006

Chain	Residue
K	VAL28
K	HIS275
K	VAL276
K	GLY277
K	ALA286
L	ASN223

---

site_id	BC6
Number of Residues	8
Details	BINDING SITE FOR RESIDUE AMP M 2007

Chain	Residue
M	ILE32
M	GLY255
M	HIS275
M	VAL276
M	GLY277
M	ASP279
M	ASN287
N	ASN223

---

site_id	BC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE AMP O 2008

Chain	Residue
O	VAL28
O	HIS275
O	VAL276
O	GLY277
O	ASN287
O	ASP328
P	ASN223

---

Functional Information from PROSITE/UniProt

site_id	PS00470
Number of Residues	20
Details	IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. SMYGTIlGNigAali.GGPGL

Chain	Residue	Details
A	SER237-LEU256
B	ASN244-LEU264

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Site: {"description":"Critical for catalysis","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	16
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P50213","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"18407956","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19779198","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	8
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"17761666","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
B	TYR142

---

site_id	CSA10
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
C	PHE136

---

site_id	CSA11
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
E	PHE136

---

site_id	CSA12
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
G	PHE136

---

site_id	CSA13
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
I	PHE136

---

site_id	CSA14
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
K	PHE136

---

site_id	CSA15
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
M	PHE136

---

site_id	CSA16
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
O	PHE136

---

site_id	CSA17
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
B	LYS189
B	ASP222

---

site_id	CSA18
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
D	LYS189
D	ASP222

---

site_id	CSA19
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
F	LYS189
F	ASP222

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
D	TYR142

---

site_id	CSA20
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
H	LYS189
H	ASP222

---

site_id	CSA21
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
J	LYS189
J	ASP222

---

site_id	CSA22
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
L	LYS189
L	ASP222

---

site_id	CSA23
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
N	LYS189
N	ASP222

---

site_id	CSA24
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
P	LYS189
P	ASP222

---

site_id	CSA25
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
A	LYS183
A	ASP217

---

site_id	CSA26
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
C	LYS183
C	ASP217

---

site_id	CSA27
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
E	LYS183
E	ASP217

---

site_id	CSA28
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
G	LYS183
G	ASP217

---

site_id	CSA29
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
I	LYS183
I	ASP217

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
F	TYR142

---

site_id	CSA30
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
K	LYS183
K	ASP217

---

site_id	CSA31
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
M	LYS183
M	ASP217

---

site_id	CSA32
Number of Residues	2
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
O	LYS183
O	ASP217

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
H	TYR142

---

site_id	CSA5
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
J	TYR142

---

site_id	CSA6
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
L	TYR142

---

site_id	CSA7
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
N	TYR142

---

site_id	CSA8
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
P	TYR142

---

site_id	CSA9
Number of Residues	1
Details	Annotated By Reference To The Literature 1a05

Chain	Residue	Details
A	PHE136

---