Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 3001 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE CNU A 1000 |
| Chain | Residue |
| A | SER183 |
| A | ILE212 |
| A | PRO228 |
| A | GLN241 |
| A | TYR243 |
| A | GLY261 |
| A | ARG262 |
| A | HOH3002 |
| A | HOH3006 |
| A | HOH3074 |
| B | ASP128 |
| B | THR132 |
| A | SER68 |
| A | ASP70 |
| A | LYS92 |
| A | HIS94 |
| A | ASP123 |
| A | ILE179 |
| A | MET182 |
| site_id | AC3 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE CNU B 1001 |
| Chain | Residue |
| A | ASP128 |
| A | ILE129 |
| A | THR132 |
| B | SER68 |
| B | ASP70 |
| B | LYS92 |
| B | HIS94 |
| B | ASP123 |
| B | ILE179 |
| B | MET182 |
| B | SER183 |
| B | ILE212 |
| B | PRO228 |
| B | GLN241 |
| B | TYR243 |
| B | GLY261 |
| B | ARG262 |
| B | HOH1002 |
| B | HOH1005 |
| B | HOH1015 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL A 2000 |
| Chain | Residue |
| A | LYS53 |
| A | ALA113 |
| A | GLU117 |
| A | PHE118 |
| A | ASP149 |
| A | HOH3099 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 2001 |
| Chain | Residue |
| A | ARG46 |
| A | HIS48 |
| A | PRO49 |
| A | SER205 |
| A | HOH3117 |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IFeDrKfaDIGnTV |
| Chain | Residue | Details |
| A | ILE120-VAL133 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"description":"For OMPdecase activity","evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QCD","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 14 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QCD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QCH","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18184586","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QCL","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| A | ASP123 | |
| A | LYS125 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| B | ASP123 | |
| B | LYS125 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| A | LYS92 | |
| A | ASP123 | |
| A | LYS125 | |
| A | ASP128 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dbt |
| Chain | Residue | Details |
| B | LYS92 | |
| B | ASP123 | |
| B | LYS125 | |
| B | ASP128 | |
