3BCC
STIGMATELLIN AND ANTIMYCIN BOUND CYTOCHROME BC1 COMPLEX FROM CHICKEN
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005739 | cellular_component | mitochondrion |
| A | 0005743 | cellular_component | mitochondrial inner membrane |
| A | 0016020 | cellular_component | membrane |
| A | 0032991 | cellular_component | protein-containing complex |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0005739 | cellular_component | mitochondrion |
| B | 0005743 | cellular_component | mitochondrial inner membrane |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
| B | 0045275 | cellular_component | respiratory chain complex III |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0005739 | cellular_component | mitochondrion |
| C | 0005743 | cellular_component | mitochondrial inner membrane |
| C | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| C | 0006979 | biological_process | response to oxidative stress |
| C | 0008121 | molecular_function | ubiquinol-cytochrome-c reductase activity |
| C | 0009055 | molecular_function | electron transfer activity |
| C | 0016020 | cellular_component | membrane |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0020037 | molecular_function | heme binding |
| C | 0022904 | biological_process | respiratory electron transport chain |
| C | 0045275 | cellular_component | respiratory chain complex III |
| C | 0046872 | molecular_function | metal ion binding |
| C | 1902600 | biological_process | proton transmembrane transport |
| D | 0009055 | molecular_function | electron transfer activity |
| D | 0020037 | molecular_function | heme binding |
| E | 0008121 | molecular_function | ubiquinol-cytochrome-c reductase activity |
| E | 0016020 | cellular_component | membrane |
| E | 0051537 | molecular_function | 2 iron, 2 sulfur cluster binding |
| F | 0005739 | cellular_component | mitochondrion |
| F | 0005743 | cellular_component | mitochondrial inner membrane |
| F | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| F | 0016020 | cellular_component | membrane |
| F | 0045275 | cellular_component | respiratory chain complex III |
| G | 0005739 | cellular_component | mitochondrion |
| G | 0005743 | cellular_component | mitochondrial inner membrane |
| G | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| G | 0016020 | cellular_component | membrane |
| G | 0021539 | biological_process | subthalamus development |
| G | 0021548 | biological_process | pons development |
| G | 0021680 | biological_process | cerebellar Purkinje cell layer development |
| G | 0021766 | biological_process | hippocampus development |
| G | 0021794 | biological_process | thalamus development |
| G | 0021854 | biological_process | hypothalamus development |
| G | 0021860 | biological_process | pyramidal neuron development |
| G | 0030901 | biological_process | midbrain development |
| G | 0045275 | cellular_component | respiratory chain complex III |
| H | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| J | 0005739 | cellular_component | mitochondrion |
| J | 0005743 | cellular_component | mitochondrial inner membrane |
| J | 0006122 | biological_process | mitochondrial electron transport, ubiquinol to cytochrome c |
| J | 0016020 | cellular_component | membrane |
| J | 0045275 | cellular_component | respiratory chain complex III |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE HEM C 381 |
| Chain | Residue |
| C | GLN45 |
| C | LEU124 |
| C | THR127 |
| C | ALA128 |
| C | GLY131 |
| C | TYR132 |
| C | LEU134 |
| C | PRO135 |
| C | HIS183 |
| C | PHE184 |
| C | PRO187 |
| C | ILE46 |
| C | GLY49 |
| C | LEU50 |
| C | LEU52 |
| C | ALA53 |
| C | ARG81 |
| C | HIS84 |
| C | ALA85 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM C 382 |
| Chain | Residue |
| C | TRP32 |
| C | PHE34 |
| C | GLY35 |
| C | SER36 |
| C | LEU38 |
| C | ALA39 |
| C | HIS98 |
| C | ILE99 |
| C | ARG101 |
| C | SER107 |
| C | TYR110 |
| C | TRP114 |
| C | GLY117 |
| C | VAL118 |
| C | LEU120 |
| C | LEU121 |
| C | THR194 |
| C | HIS197 |
| C | LEU201 |
| C | ASN207 |
| C | AMY384 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HEM D 242 |
| Chain | Residue |
| D | VAL36 |
| D | CYS37 |
| D | CYS40 |
| D | HIS41 |
| D | ASN105 |
| D | PRO110 |
| D | PRO111 |
| D | ARG120 |
| D | TYR126 |
| D | PHE153 |
| D | ILE158 |
| D | GLY159 |
| D | MET160 |
| D | PRO163 |
| D | VAL186 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FES E 197 |
| Chain | Residue |
| E | CYS139 |
| E | HIS141 |
| E | CYS144 |
| E | CYS158 |
| E | CYS160 |
| E | HIS161 |
| E | GLY162 |
| E | SER163 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SIG C 383 |
| Chain | Residue |
| C | MET125 |
| C | PHE129 |
| C | VAL130 |
| C | VAL146 |
| C | ILE147 |
| C | LEU182 |
| C | PRO271 |
| C | PHE275 |
| C | TYR279 |
| C | LEU295 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE AMY C 384 |
| Chain | Residue |
| C | SER18 |
| C | TRP32 |
| C | ASN33 |
| C | GLY35 |
| C | SER36 |
| C | ALA39 |
| C | LEU42 |
| C | MET43 |
| C | ALA191 |
| C | THR194 |
| C | ILE195 |
| C | LEU198 |
| C | PHE221 |
| C | TYR225 |
| C | LYS228 |
| C | ASP229 |
| C | HEM382 |
Functional Information from PROSITE/UniProt
| site_id | PS00143 |
| Number of Residues | 24 |
| Details | INSULINASE Insulinase family, zinc-binding region signature. GsryenssnlGtSHLLRLAsSlTT |
| Chain | Residue | Details |
| B | GLY54-THR77 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 19 |
| Details | TOPO_DOM: Mitochondrial matrix => ECO:0000269|PubMed:9651245 |
| Chain | Residue | Details |
| J | ALA2-ALA21 | |
| D | GLU124 | |
| C | TRP114-LEU134 | |
| C | PHE179-THR199 | |
| C | PHE227-SER247 | |
| C | LEU289-HIS309 | |
| C | LEU321-SER341 | |
| C | PHE348-PRO368 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:9651245 |
| Chain | Residue | Details |
| J | LEU22-ASN47 | |
| F | TYR83 | |
| F | GLU96 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-succinyllysine; alternate => ECO:0000250|UniProtKB:Q9CQ69 |
| Chain | Residue | Details |
| G | GLY33 | |
| F | PRO88 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9651245, ECO:0007744|PDB:1BE3, ECO:0007744|PDB:1BGY |
| Chain | Residue | Details |
| E | CYS139 | |
| E | HIS141 | |
| E | CYS158 | |
| E | HIS161 | |
| E | SER163 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:21575592, ECO:0000269|PubMed:22690928, ECO:0000269|PubMed:9565029, ECO:0007744|PDB:1BCC, ECO:0007744|PDB:3CWB, ECO:0007744|PDB:3H1K, ECO:0007744|PDB:3L72 |
| Chain | Residue | Details |
| C | HIS202 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ndo |
| Chain | Residue | Details |
| E | HIS161 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ndo |
| Chain | Residue | Details |
| A | GLU60 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1ndo |
| Chain | Residue | Details |
| B | ARG70 |
