3BCA

Crystal structure of mouse selenocysteine synthase, sodium iodide soak

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001717	biological_process	conversion of seryl-tRNAsec to selenocys-tRNAsec
A	0016740	molecular_function	transferase activity
A	0098621	molecular_function	O-phosphoseryl-tRNA(Sec) selenium transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 501

Chain	Residue
A	ARG75
A	HOH797

---

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 502

Chain	Residue
A	LYS173
A	HOH624

---

site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 503

Chain	Residue
A	GLY312

---

site_id	AC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 505

Chain	Residue
A	LYS158

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 507

Chain	Residue
A	GLY68
A	GLN399

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 508

Chain	Residue
A	ARG234
A	THR379
A	LEU202

---

site_id	AC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 509

Chain	Residue
A	ALA80

---

site_id	AC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 511

Chain	Residue
A	ASN428

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 512

Chain	Residue
A	LYS177

---

site_id	BC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 513

Chain	Residue
A	LYS177

---

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 514

Chain	Residue
A	GLY213
A	GLU215

---

site_id	BC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 515

Chain	Residue
A	HOH688

---

site_id	BC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 516

Chain	Residue
A	SER259
A	ARG341
A	LYS342

---

site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 518

Chain	Residue
A	ARG271

---

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 519

Chain	Residue
A	LYS456

---

site_id	BC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 520

Chain	Residue
A	CYS41
A	ASN124
A	CYS331

---

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 521

Chain	Residue
A	LYS127

---

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 522

Chain	Residue
A	LYS339
A	HOH731

---

site_id	CC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 523

Chain	Residue
A	THR350
A	GLN351

---

site_id	CC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 524

Chain	Residue
A	CYS431

---

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 525

Chain	Residue
A	THR389
A	PRO407

---

site_id	CC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 526

Chain	Residue
A	HOH657

---

site_id	CC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 527

Chain	Residue
A	ASP455

---

site_id	CC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE IOD A 528

Chain	Residue
A	SER393
A	THR397
A	ARG398
A	HOH666

---

site_id	CC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 533

Chain	Residue
A	ASN119
A	HOH654

---

site_id	CC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 535

Chain	Residue
A	MET444
A	GLN445

---

site_id	CC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 536

Chain	Residue
A	HOH580
A	HOH620

---

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD A 537

Chain	Residue
A	GLU43
A	SER332
A	ARG335

---

site_id	DC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 538

Chain	Residue
A	ARG453

---

site_id	DC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 539

Chain	Residue
A	VAL79

---

site_id	DC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 540

Chain	Residue
A	GLY96
A	SER112

---

site_id	DC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 541

Chain	Residue
A	SER112

---

site_id	DC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 543

Chain	Residue
A	HOH640

---

site_id	DC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 546

Chain	Residue
A	LYS163
A	HIS216

---

site_id	DC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 547

Chain	Residue
A	LYS261
A	CYS262

---

site_id	DC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 549

Chain	Residue
A	GLU48
A	SER49

---

site_id	EC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 551

Chain	Residue
A	GLU29

---

site_id	EC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 552

Chain	Residue
A	SER133
A	GLN267

---

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 555

Chain	Residue
A	SER260
A	HOH683

---

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 556

Chain	Residue
A	LYS208

---

site_id	EC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 557

Chain	Residue
A	LYS116
A	ILE117

---

site_id	EC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 559

Chain	Residue
A	LYS386

---

site_id	EC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 560

Chain	Residue
A	SER393

---

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 561

Chain	Residue
A	CYS137

---

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 562

Chain	Residue
A	GLN304

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"18093968","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Site: {"description":"May act as a substrate filter by repelling compounds with a negatively charged alpha-carboxylate","evidences":[{"source":"PubMed","id":"18093968","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"N6-(pyridoxal phosphate)lysine","evidences":[{"source":"PubMed","id":"18093968","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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